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- W4313406780 endingPage "e005514" @default.
- W4313406780 startingPage "e005514" @default.
- W4313406780 abstract "The complexity of cancer immunotherapy (CIT) demands reliable preclinical models to successfully translate study findings to the clinics. Non-human primates (NHPs; here referring to rhesus and cynomolgus macaques) share broad similarities with humans including physiology, genetic homology, and importantly also immune cell populations, immune regulatory mechanisms, and protein targets for CIT. Furthermore, NHP naturally develop cancers such as colorectal and breast cancer with an incidence, pathology, and age pattern comparable to humans. Thus, these tumor-bearing monkeys (TBMs) have the potential to bridge the experimental gap between early preclinical cancer models and patients with human cancer. This review presents our current knowledge of NHP immunology, the incidence and features of naturally-occurring cancers in NHP, and recent TBM trials investigating CIT to provide a scientific rationale for this unique model for human cancer." @default.
- W4313406780 created "2023-01-06" @default.
- W4313406780 creator A5002653345 @default.
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- W4313406780 creator A5042409986 @default.
- W4313406780 creator A5068860618 @default.
- W4313406780 creator A5079916764 @default.
- W4313406780 date "2023-01-01" @default.
- W4313406780 modified "2023-10-05" @default.
- W4313406780 title "Spontaneous, naturally occurring cancers in non-human primates as a translational model for cancer immunotherapy" @default.
- W4313406780 cites W1492166511 @default.
- W4313406780 cites W1547507373 @default.
- W4313406780 cites W1572743872 @default.
- W4313406780 cites W161426596 @default.
- W4313406780 cites W1625302502 @default.
- W4313406780 cites W1938556206 @default.
- W4313406780 cites W1968167186 @default.
- W4313406780 cites W1968684935 @default.
- W4313406780 cites W1970565131 @default.
- W4313406780 cites W1970766078 @default.
- W4313406780 cites W1986509940 @default.
- W4313406780 cites W1997849135 @default.
- W4313406780 cites W1999022079 @default.
- W4313406780 cites W1999679155 @default.
- W4313406780 cites W2010091139 @default.
- W4313406780 cites W2019812267 @default.
- W4313406780 cites W2024222590 @default.
- W4313406780 cites W2034668950 @default.
- W4313406780 cites W2046127379 @default.
- W4313406780 cites W2049927822 @default.
- W4313406780 cites W2049931658 @default.
- W4313406780 cites W2050680529 @default.
- W4313406780 cites W2055173005 @default.
- W4313406780 cites W2058118470 @default.
- W4313406780 cites W2060886652 @default.
- W4313406780 cites W2073432366 @default.
- W4313406780 cites W2076743146 @default.
- W4313406780 cites W2078869001 @default.
- W4313406780 cites W2082323859 @default.
- W4313406780 cites W2099609050 @default.
- W4313406780 cites W2104601608 @default.
- W4313406780 cites W2107021471 @default.
- W4313406780 cites W2124580054 @default.
- W4313406780 cites W2125570957 @default.
- W4313406780 cites W2134879362 @default.
- W4313406780 cites W2138866256 @default.
- W4313406780 cites W2154774881 @default.
- W4313406780 cites W2156349162 @default.
- W4313406780 cites W2156703175 @default.
- W4313406780 cites W2157440402 @default.
- W4313406780 cites W2159819132 @default.
- W4313406780 cites W2161066867 @default.
- W4313406780 cites W2169733452 @default.
- W4313406780 cites W2170104026 @default.
- W4313406780 cites W2172089049 @default.
- W4313406780 cites W2186419937 @default.
- W4313406780 cites W2304485006 @default.
- W4313406780 cites W2330872912 @default.
- W4313406780 cites W2467415540 @default.
- W4313406780 cites W2470172036 @default.
- W4313406780 cites W249909562 @default.
- W4313406780 cites W2516271598 @default.
- W4313406780 cites W2560704457 @default.
- W4313406780 cites W2590417095 @default.
- W4313406780 cites W2593916983 @default.
- W4313406780 cites W2617384231 @default.
- W4313406780 cites W2742193031 @default.
- W4313406780 cites W2747774814 @default.
- W4313406780 cites W2777192533 @default.
- W4313406780 cites W2783928952 @default.
- W4313406780 cites W2790803947 @default.
- W4313406780 cites W2791043878 @default.
- W4313406780 cites W2794190791 @default.
- W4313406780 cites W2889646458 @default.
- W4313406780 cites W2889746019 @default.
- W4313406780 cites W2898974797 @default.
- W4313406780 cites W2900752818 @default.
- W4313406780 cites W2910245285 @default.
- W4313406780 cites W2912099984 @default.
- W4313406780 cites W2930582547 @default.
- W4313406780 cites W2933814945 @default.
- W4313406780 cites W2952816064 @default.
- W4313406780 cites W2971174770 @default.
- W4313406780 cites W2974947353 @default.
- W4313406780 cites W3000339487 @default.
- W4313406780 cites W3013236696 @default.
- W4313406780 cites W3024551702 @default.
- W4313406780 cites W3024966661 @default.
- W4313406780 cites W3081906982 @default.
- W4313406780 cites W3087779713 @default.
- W4313406780 cites W3091399767 @default.
- W4313406780 cites W3091922182 @default.
- W4313406780 cites W3094094861 @default.
- W4313406780 cites W3095297211 @default.
- W4313406780 cites W3098592536 @default.
- W4313406780 cites W3105380215 @default.
- W4313406780 cites W3120681370 @default.
- W4313406780 cites W3162774340 @default.