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- W4313407846 abstract "The mammalian body typically consists of trillions of cells. These cells are the basic structural and functional units of a mammalian body. Together, these cells form tissues, tissues form organs, and organs collectively build up systems, constructing a whole body. The basis of cell theory states that mammalian cells originate from the pre-existent mother cells by the simple process of cell division (mitosis/meiosis). Thus, cell culture not only aims toward understanding the basic steps necessary for physiological processes involved in regular homeostasis in the body but also understanding various pathophysiological or diseased conditions associated with cellular dysfunction and their regulation by synthetic drugs/toxins, etc. Technically, mammalian cell culture is defined as the ongoing process by which cells are isolated from a mammalian body (typically from a specific tissue or organ) and are grown in vitro with a constant supply of synthetic nutrients under controlled laboratory conditions of optimum pH, temperature, and humidity in a CO2 incubator/bioreactor. Nowadays, the term tissue culture is often used interchangeably with cell culture. In modern times, cultured mammalian cells are widely used for the bulk production of antibodies, vaccines, cytokines, growth factors, hormones, and other proteins in demand. To understand mammalian cell culture, it is not only important to gain knowledge regarding the basic concept and the ardent contributions of various scientists towards the development of this unique technology but it also requires selecting and validating specific experimental conditions for cell culture." @default.
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- W4313407846 date "2023-01-01" @default.
- W4313407846 modified "2023-10-12" @default.
- W4313407846 title "Mammalian Cell Culture: An Overview" @default.
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- W4313407846 doi "https://doi.org/10.1007/978-981-19-1731-8_1-1" @default.
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