Matches in SemOpenAlex for { <https://semopenalex.org/work/W4313409904> ?p ?o ?g. }
Showing items 1 to 69 of
69
with 100 items per page.
- W4313409904 endingPage "140" @default.
- W4313409904 startingPage "140" @default.
- W4313409904 abstract "Melinjo leaves has several benefits as antidiabetic, antihyperglycemia, antioxidant and diuretic. In this experiment the acute toxicity test of ethanol extract of melinjo (Gnetum gnemon L). leaves on male white rats of wistar strain with fixed dose procedure method. The result of the screening of the phytochemical showed that the leaves of beluntas contained alcaloid, flavonoid, saponin, fenolic, and tanin. Ethanol extract of melinjo leaves was obtained by maceration using ethanol 70%. From the observational study, the dose 2000 mg/kg BW was chosen as starting dose for the main study. Experimental animal subject used in the main study were 10 male white rats of wistar which were divided into 2 group, normal group and treatment group with a dose of 2000 mg/kgBW. The result showed that there were no death or toxicity sign in all experimental animals. During the 14 days observation period, there were no significant changes in body weight of rats either in normal control group and treatmen group with a dose of 2000 mg/kg BW (p>0.05). Melinjo leaves had no effect on the macroscopic organs of liver, kidneys and heart of the test animals (p>0.05). The average level of biochemical parameters in the normal group is SGOT 54.13±11.428 U/L, SGPT 47.476±21.655 U/L, creatinine 0.632±0.199 mg/dL, and urea 14.46±2.267 mg/dL, while the 2000 mg/kg BW dose group is SGOT 60.192±14.198 U/L, SGPT 55.968±22.998 U/L, creatinine 0.756±0.204 mg/dL, and urea 16±2.561 mg/dL. It showed that the ethanol extract of melinjo leaves with a dose of 2000 mg/kgBW are the category of practically non-toxic." @default.
- W4313409904 created "2023-01-06" @default.
- W4313409904 creator A5013877937 @default.
- W4313409904 creator A5017599042 @default.
- W4313409904 creator A5046976769 @default.
- W4313409904 creator A5081905613 @default.
- W4313409904 date "2022-12-29" @default.
- W4313409904 modified "2023-09-30" @default.
- W4313409904 title "Accute Toxicity Of Extract From Melinjo (Gnetum Gnemon L) Leaf With Fixed Dose Procedure Method" @default.
- W4313409904 doi "https://doi.org/10.24198/ijpst.v9i3.33683" @default.
- W4313409904 hasPublicationYear "2022" @default.
- W4313409904 type Work @default.
- W4313409904 citedByCount "0" @default.
- W4313409904 crossrefType "journal-article" @default.
- W4313409904 hasAuthorship W4313409904A5013877937 @default.
- W4313409904 hasAuthorship W4313409904A5017599042 @default.
- W4313409904 hasAuthorship W4313409904A5046976769 @default.
- W4313409904 hasAuthorship W4313409904A5081905613 @default.
- W4313409904 hasBestOaLocation W43134099041 @default.
- W4313409904 hasConcept C116263406 @default.
- W4313409904 hasConcept C126322002 @default.
- W4313409904 hasConcept C159985019 @default.
- W4313409904 hasConcept C185592680 @default.
- W4313409904 hasConcept C192562407 @default.
- W4313409904 hasConcept C195475562 @default.
- W4313409904 hasConcept C2778004101 @default.
- W4313409904 hasConcept C2779054382 @default.
- W4313409904 hasConcept C2780306776 @default.
- W4313409904 hasConcept C2780365088 @default.
- W4313409904 hasConcept C29730261 @default.
- W4313409904 hasConcept C55493867 @default.
- W4313409904 hasConcept C556039675 @default.
- W4313409904 hasConcept C71924100 @default.
- W4313409904 hasConcept C74940592 @default.
- W4313409904 hasConceptScore W4313409904C116263406 @default.
- W4313409904 hasConceptScore W4313409904C126322002 @default.
- W4313409904 hasConceptScore W4313409904C159985019 @default.
- W4313409904 hasConceptScore W4313409904C185592680 @default.
- W4313409904 hasConceptScore W4313409904C192562407 @default.
- W4313409904 hasConceptScore W4313409904C195475562 @default.
- W4313409904 hasConceptScore W4313409904C2778004101 @default.
- W4313409904 hasConceptScore W4313409904C2779054382 @default.
- W4313409904 hasConceptScore W4313409904C2780306776 @default.
- W4313409904 hasConceptScore W4313409904C2780365088 @default.
- W4313409904 hasConceptScore W4313409904C29730261 @default.
- W4313409904 hasConceptScore W4313409904C55493867 @default.
- W4313409904 hasConceptScore W4313409904C556039675 @default.
- W4313409904 hasConceptScore W4313409904C71924100 @default.
- W4313409904 hasConceptScore W4313409904C74940592 @default.
- W4313409904 hasIssue "3" @default.
- W4313409904 hasLocation W43134099041 @default.
- W4313409904 hasOpenAccess W4313409904 @default.
- W4313409904 hasPrimaryLocation W43134099041 @default.
- W4313409904 hasRelatedWork W2246823946 @default.
- W4313409904 hasRelatedWork W2556792895 @default.
- W4313409904 hasRelatedWork W2735577872 @default.
- W4313409904 hasRelatedWork W2788261216 @default.
- W4313409904 hasRelatedWork W2885904309 @default.
- W4313409904 hasRelatedWork W2904783307 @default.
- W4313409904 hasRelatedWork W2997917621 @default.
- W4313409904 hasRelatedWork W3038873168 @default.
- W4313409904 hasRelatedWork W3217056369 @default.
- W4313409904 hasRelatedWork W4229335346 @default.
- W4313409904 hasVolume "9" @default.
- W4313409904 isParatext "false" @default.
- W4313409904 isRetracted "false" @default.
- W4313409904 workType "article" @default.