FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4313415027> ?p ?o ?g. }

• W4313415027 endingPage "116" @default.
• W4313415027 startingPage "116" @default.
• W4313415027 abstract "Primary membrane nephropathy (PMN) and IgA nephropathy (IgAN) are the most common glomerular diseases in China. Because of different pathogenesis, prognosis is significantly different. When the two diseases coexist (PMN/IgAN), the clinicopathological manifestations and prognosis remain unclear. In the present study, we analyzed the clinicopathological characteristics of PMN/IgAN patients, with only IgA deposition (PMN/IgA deposition) patients as controls. Galactose-deficient IgA1(KM55) and M-type Phospholipase A2 Receptor(PLA2R), both in circulation and renal tissues, were detected. Furthermore, prognosis of PMN/IgAN was explored. We found that PMN/IgAN also had some clinical features of IgAN in addition to PMN, such as higher serum albumin, along with a similar heavy proteinuria and lower titers of serum anti-PLA2R antibody. The positive rate of glomerular KM55 in PMN/IgAN was 23.5% (20/85), and 0% (0/29) in PMN/IgA deposition. Among those glomerular KM55 positive patients, KM55 and IgA colocalized mainly along the glomerular mesangial and capillary areas. Unfortunately, there was no significant difference in serum level of Gd-IgA1 between KM55+ and KM55- subgroups in PMN/IgAN patients, similar to the PMN/IgA deposition group. Notably, glomerular KM55 positive may predict a poorer prognosis in PMN/IgAN patients. In conclusion, our study suggested that, when glomerular KM55 staining was positive, this special coexisting PMN/IgAN disorder was prone to have more characteristics of IgAN besides PMN, and may predict poorer prognosis, while the mechanism requires further investigation." @default.
• W4313415027 created "2023-01-06" @default.
• W4313415027 creator A5011205445 @default.
• W4313415027 creator A5028516138 @default.
• W4313415027 creator A5033015509 @default.
• W4313415027 creator A5050587936 @default.
• W4313415027 creator A5066195526 @default.
• W4313415027 creator A5068178447 @default.
• W4313415027 creator A5068636088 @default.
• W4313415027 creator A5070120817 @default.
• W4313415027 creator A5088640926 @default.
• W4313415027 date "2022-12-28" @default.
• W4313415027 modified "2023-10-14" @default.
• W4313415027 title "Glomerular Galactose-Deficient IgA1(KM55) Positive May Predict Poorer Prognosis in Coexisting Primary Membranous Nephropathy and IgA Nephropathy Patients" @default.
• W4313415027 cites W2052245163 @default.
• W4313415027 cites W2140565611 @default.
• W4313415027 cites W2141077533 @default.
• W4313415027 cites W2141275524 @default.
• W4313415027 cites W2142334741 @default.
• W4313415027 cites W2155965977 @default.
• W4313415027 cites W2290231466 @default.
• W4313415027 cites W2405467493 @default.
• W4313415027 cites W2466716896 @default.
• W4313415027 cites W2586394131 @default.
• W4313415027 cites W2594551887 @default.
• W4313415027 cites W2607031541 @default.
• W4313415027 cites W2617482626 @default.
• W4313415027 cites W2784057818 @default.
• W4313415027 cites W2796160310 @default.
• W4313415027 cites W2805831889 @default.
• W4313415027 cites W2943790844 @default.
• W4313415027 cites W2965853783 @default.
• W4313415027 cites W2969644909 @default.
• W4313415027 cites W2978224178 @default.
• W4313415027 cites W3106601191 @default.
• W4313415027 cites W3153698692 @default.
• W4313415027 cites W3200514417 @default.
• W4313415027 cites W4200564707 @default.
• W4313415027 cites W4221070008 @default.
• W4313415027 cites W4225000320 @default.
• W4313415027 cites W4226265026 @default.
• W4313415027 cites W4282003310 @default.
• W4313415027 cites W4300751677 @default.
• W4313415027 doi "https://doi.org/10.3390/cells12010116" @default.
• W4313415027 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36611910" @default.
• W4313415027 hasPublicationYear "2022" @default.
• W4313415027 type Work @default.
• W4313415027 citedByCount "0" @default.
• W4313415027 crossrefType "journal-article" @default.
• W4313415027 hasAuthorship W4313415027A5011205445 @default.
• W4313415027 hasAuthorship W4313415027A5028516138 @default.
• W4313415027 hasAuthorship W4313415027A5033015509 @default.
• W4313415027 hasAuthorship W4313415027A5050587936 @default.
• W4313415027 hasAuthorship W4313415027A5066195526 @default.
• W4313415027 hasAuthorship W4313415027A5068178447 @default.
• W4313415027 hasAuthorship W4313415027A5068636088 @default.
• W4313415027 hasAuthorship W4313415027A5070120817 @default.
• W4313415027 hasAuthorship W4313415027A5088640926 @default.
• W4313415027 hasBestOaLocation W43134150271 @default.
• W4313415027 hasConcept C126322002 @default.
• W4313415027 hasConcept C134018914 @default.
• W4313415027 hasConcept C142724271 @default.
• W4313415027 hasConcept C159641895 @default.
• W4313415027 hasConcept C159654299 @default.
• W4313415027 hasConcept C203014093 @default.
• W4313415027 hasConcept C2775946357 @default.
• W4313415027 hasConcept C2779102806 @default.
• W4313415027 hasConcept C2779561371 @default.
• W4313415027 hasConcept C2780091579 @default.
• W4313415027 hasConcept C2780368995 @default.
• W4313415027 hasConcept C2780898057 @default.
• W4313415027 hasConcept C2780942790 @default.
• W4313415027 hasConcept C2781184683 @default.
• W4313415027 hasConcept C555293320 @default.
• W4313415027 hasConcept C71924100 @default.
• W4313415027 hasConcept C90924648 @default.
• W4313415027 hasConceptScore W4313415027C126322002 @default.
• W4313415027 hasConceptScore W4313415027C134018914 @default.
• W4313415027 hasConceptScore W4313415027C142724271 @default.
• W4313415027 hasConceptScore W4313415027C159641895 @default.
• W4313415027 hasConceptScore W4313415027C159654299 @default.
• W4313415027 hasConceptScore W4313415027C203014093 @default.
• W4313415027 hasConceptScore W4313415027C2775946357 @default.
• W4313415027 hasConceptScore W4313415027C2779102806 @default.
• W4313415027 hasConceptScore W4313415027C2779561371 @default.
• W4313415027 hasConceptScore W4313415027C2780091579 @default.
• W4313415027 hasConceptScore W4313415027C2780368995 @default.
• W4313415027 hasConceptScore W4313415027C2780898057 @default.
• W4313415027 hasConceptScore W4313415027C2780942790 @default.
• W4313415027 hasConceptScore W4313415027C2781184683 @default.
• W4313415027 hasConceptScore W4313415027C555293320 @default.
• W4313415027 hasConceptScore W4313415027C71924100 @default.
• W4313415027 hasConceptScore W4313415027C90924648 @default.
• W4313415027 hasIssue "1" @default.
• W4313415027 hasLocation W43134150271 @default.
• W4313415027 hasLocation W43134150272 @default.
• W4313415027 hasLocation W43134150273 @default.
• W4313415027 hasOpenAccess W4313415027 @default.

• next