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- W4313441772 abstract "Gastrointestinal tumors are the most common cancers with the highest morbidity and mortality worldwide. Surgery accompanied by chemotherapy, radiotherapy and targeted therapy remains the first option for gastrointestinal tumors. However, poor specificity for tumor cells of these postoperative treatments often leads to severe side effects and poor prognosis. Tumor immunotherapy, including checkpoint blockade and tumor vaccines, has developed rapidly in recent years, showing good curative effects and minimal side effects in the treatment of gastrointestinal tumors. National Comprehensive Cancer Network guidelines recommend tumor immunotherapy as part of the treatment of gastrointestinal tumors. However, the heterogeneity of tumor cells, complicacy of the tumor microenvironment and poor tumor immunogenicity hamper the effectiveness of tumor immunotherapy. Hydrogels, defined as three-dimensional, hydrophilic, and water-insoluble polymeric networks, could significantly improve the overall response rate of immunotherapy due to their superior drug loading efficacy, controlled release and drug codelivery ability. In this article, we briefly describe the research progress made in recent years on hydrogel delivery systems in immunotherapy for gastrointestinal tumors and discuss the potential future application prospects and challenges to provide a reference for the clinical application of hydrogels in tumor immunotherapy." @default.
- W4313441772 created "2023-01-06" @default.
- W4313441772 creator A5005985148 @default.
- W4313441772 creator A5016497715 @default.
- W4313441772 creator A5018073672 @default.
- W4313441772 creator A5040248676 @default.
- W4313441772 creator A5047979143 @default.
- W4313441772 creator A5087592842 @default.
- W4313441772 creator A5088947532 @default.
- W4313441772 date "2023-01-01" @default.
- W4313441772 modified "2023-09-27" @default.
- W4313441772 title "Progress in the application of hydrogels in immunotherapy of gastrointestinal tumors" @default.
- W4313441772 cites W1543079591 @default.
- W4313441772 cites W1577612079 @default.
- W4313441772 cites W1913328895 @default.
- W4313441772 cites W1946970680 @default.
- W4313441772 cites W1972494701 @default.
- W4313441772 cites W1976041409 @default.
- W4313441772 cites W1977857189 @default.
- W4313441772 cites W1983923482 @default.
- W4313441772 cites W1983986735 @default.
- W4313441772 cites W1990602451 @default.
- W4313441772 cites W1994969460 @default.
- W4313441772 cites W2011335750 @default.
- W4313441772 cites W2016732129 @default.
- W4313441772 cites W2024306244 @default.
- W4313441772 cites W2025038288 @default.
- W4313441772 cites W2033577259 @default.
- W4313441772 cites W2048893610 @default.
- W4313441772 cites W2060420887 @default.
- W4313441772 cites W2060870743 @default.
- W4313441772 cites W2066511695 @default.
- W4313441772 cites W2066671159 @default.
- W4313441772 cites W2067632426 @default.
- W4313441772 cites W2087312216 @default.
- W4313441772 cites W2097995306 @default.
- W4313441772 cites W2104172231 @default.
- W4313441772 cites W2132831385 @default.
- W4313441772 cites W2134433047 @default.
- W4313441772 cites W2142447995 @default.
- W4313441772 cites W2149748445 @default.
- W4313441772 cites W2163326536 @default.
- W4313441772 cites W2167043340 @default.
- W4313441772 cites W2171261881 @default.
- W4313441772 cites W2202349529 @default.
- W4313441772 cites W2279561773 @default.
- W4313441772 cites W2289712604 @default.
- W4313441772 cites W2302088846 @default.
- W4313441772 cites W2466078731 @default.
- W4313441772 cites W2524283095 @default.
- W4313441772 cites W2533513686 @default.
- W4313441772 cites W2557800547 @default.
- W4313441772 cites W2558485988 @default.
- W4313441772 cites W2560367415 @default.
- W4313441772 cites W2564809671 @default.
- W4313441772 cites W2566704745 @default.
- W4313441772 cites W2581827633 @default.
- W4313441772 cites W2587677103 @default.
- W4313441772 cites W2587691649 @default.
- W4313441772 cites W2608075525 @default.
- W4313441772 cites W2619357018 @default.
- W4313441772 cites W2626179676 @default.
- W4313441772 cites W2743388258 @default.
- W4313441772 cites W2774113098 @default.
- W4313441772 cites W2796582438 @default.
- W4313441772 cites W2801067660 @default.
- W4313441772 cites W2801309958 @default.
- W4313441772 cites W2802862526 @default.
- W4313441772 cites W2803043384 @default.
- W4313441772 cites W2884102832 @default.
- W4313441772 cites W2894717949 @default.
- W4313441772 cites W2895357007 @default.
- W4313441772 cites W2908574415 @default.
- W4313441772 cites W2911123976 @default.
- W4313441772 cites W2911543360 @default.
- W4313441772 cites W2912711791 @default.
- W4313441772 cites W2937946645 @default.
- W4313441772 cites W2941481939 @default.
- W4313441772 cites W2953515119 @default.
- W4313441772 cites W2963094884 @default.
- W4313441772 cites W2964578707 @default.
- W4313441772 cites W2966348083 @default.
- W4313441772 cites W2969758768 @default.
- W4313441772 cites W2971178217 @default.
- W4313441772 cites W2974984990 @default.
- W4313441772 cites W2976901627 @default.
- W4313441772 cites W2979919874 @default.
- W4313441772 cites W2986629061 @default.
- W4313441772 cites W2989796631 @default.
- W4313441772 cites W2996852725 @default.
- W4313441772 cites W2998765636 @default.
- W4313441772 cites W3000339487 @default.
- W4313441772 cites W3004611567 @default.
- W4313441772 cites W3007507803 @default.
- W4313441772 cites W3008278663 @default.
- W4313441772 cites W3009193015 @default.
- W4313441772 cites W3015079516 @default.
- W4313441772 cites W3015729319 @default.
- W4313441772 cites W3017473937 @default.
- W4313441772 cites W3028523516 @default.