FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4313442029> ?p ?o ?g. }

• W4313442029 endingPage "265" @default.
• W4313442029 startingPage "252" @default.
• W4313442029 abstract "Dynamic interactions between the subregions of the hippocampus are required for the encoding and consolidation of memory. While the interplay and contributions of the CA1 and CA3 regions are well understood, we continue to learn more about how CA2 differentially contributes to the organization of network function. For example, CA2 place cells have been reported to be less spatially tuned during exploration, but uniquely capable of coding place while an animal stops. Here we applied chemogenetics to transiently silence CA2 pyramidal cells and found that CA2 influences hippocampal dynamics in a state-dependent manner. We find that during rest, CA2 inhibition reduces synchronization across regions (CA1, CA2, CA3) and frequency bands (low-gamma- and ripple-band). Moreover, during new learning CA1 place field formation is slower in the absence of CA2 transmission and during pausing, CA1 pyramidal cells are less excitable without CA2 drive. On the network level, a novel convolutional neural network (SpikeDecoder) was employed to show subregion and state-dependent changes in spatial coding that agree with our observations on the single cell level. Together these data suggest additional novel roles for CA2 in governing and differentiating hippocampal dynamics under discrete behavioral states." @default.
• W4313442029 created "2023-01-06" @default.
• W4313442029 creator A5029155475 @default.
• W4313442029 creator A5029667848 @default.
• W4313442029 creator A5078685172 @default.
• W4313442029 date "2023-01-03" @default.
• W4313442029 modified "2023-10-13" @default.
• W4313442029 title "Behavioral status modulates <scp>CA2</scp> influence on hippocampal network dynamics" @default.
• W4313442029 cites W1770958704 @default.
• W4313442029 cites W1779226031 @default.
• W4313442029 cites W1966403223 @default.
• W4313442029 cites W1966641148 @default.
• W4313442029 cites W1974367810 @default.
• W4313442029 cites W1981998044 @default.
• W4313442029 cites W1984214648 @default.
• W4313442029 cites W1989932452 @default.
• W4313442029 cites W2005317473 @default.
• W4313442029 cites W2011504521 @default.
• W4313442029 cites W2046999866 @default.
• W4313442029 cites W2054347272 @default.
• W4313442029 cites W2067332645 @default.
• W4313442029 cites W2071678249 @default.
• W4313442029 cites W2079161053 @default.
• W4313442029 cites W2079968698 @default.
• W4313442029 cites W2082389353 @default.
• W4313442029 cites W2092284040 @default.
• W4313442029 cites W2098371930 @default.
• W4313442029 cites W2112575160 @default.
• W4313442029 cites W2116341396 @default.
• W4313442029 cites W2170097553 @default.
• W4313442029 cites W2170430044 @default.
• W4313442029 cites W2227829864 @default.
• W4313442029 cites W2264119724 @default.
• W4313442029 cites W2265785955 @default.
• W4313442029 cites W2288876215 @default.
• W4313442029 cites W2414441136 @default.
• W4313442029 cites W2514879313 @default.
• W4313442029 cites W2610785804 @default.
• W4313442029 cites W2763166029 @default.
• W4313442029 cites W2805835150 @default.
• W4313442029 cites W2899285839 @default.
• W4313442029 cites W2901918057 @default.
• W4313442029 cites W2950904558 @default.
• W4313442029 cites W2998579682 @default.
• W4313442029 cites W3011497024 @default.
• W4313442029 cites W3087859979 @default.
• W4313442029 cites W3148616091 @default.
• W4313442029 cites W3161871721 @default.
• W4313442029 cites W3189792013 @default.
• W4313442029 cites W3201221109 @default.
• W4313442029 cites W4247532959 @default.
• W4313442029 cites W4251940122 @default.
• W4313442029 doi "https://doi.org/10.1002/hipo.23498" @default.
• W4313442029 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36594707" @default.
• W4313442029 hasPublicationYear "2023" @default.
• W4313442029 type Work @default.
• W4313442029 citedByCount "2" @default.
• W4313442029 countsByYear W43134420292023 @default.
• W4313442029 crossrefType "journal-article" @default.
• W4313442029 hasAuthorship W4313442029A5029155475 @default.
• W4313442029 hasAuthorship W4313442029A5029667848 @default.
• W4313442029 hasAuthorship W4313442029A5078685172 @default.
• W4313442029 hasConcept C118615104 @default.
• W4313442029 hasConcept C123757187 @default.
• W4313442029 hasConcept C148762608 @default.
• W4313442029 hasConcept C15744967 @default.
• W4313442029 hasConcept C169760540 @default.
• W4313442029 hasConcept C185592680 @default.
• W4313442029 hasConcept C2781161787 @default.
• W4313442029 hasConcept C2781369091 @default.
• W4313442029 hasConcept C33923547 @default.
• W4313442029 hasConcept C48455012 @default.
• W4313442029 hasConceptScore W4313442029C118615104 @default.
• W4313442029 hasConceptScore W4313442029C123757187 @default.
• W4313442029 hasConceptScore W4313442029C148762608 @default.
• W4313442029 hasConceptScore W4313442029C15744967 @default.
• W4313442029 hasConceptScore W4313442029C169760540 @default.
• W4313442029 hasConceptScore W4313442029C185592680 @default.
• W4313442029 hasConceptScore W4313442029C2781161787 @default.
• W4313442029 hasConceptScore W4313442029C2781369091 @default.
• W4313442029 hasConceptScore W4313442029C33923547 @default.
• W4313442029 hasConceptScore W4313442029C48455012 @default.
• W4313442029 hasFunder F4320320912 @default.
• W4313442029 hasFunder F4320334764 @default.
• W4313442029 hasIssue "3" @default.
• W4313442029 hasLocation W43134420291 @default.
• W4313442029 hasLocation W43134420292 @default.
• W4313442029 hasOpenAccess W4313442029 @default.
• W4313442029 hasPrimaryLocation W43134420291 @default.
• W4313442029 hasRelatedWork W17166845 @default.
• W4313442029 hasRelatedWork W1973915385 @default.
• W4313442029 hasRelatedWork W2047165031 @default.
• W4313442029 hasRelatedWork W2061706623 @default.
• W4313442029 hasRelatedWork W2096876955 @default.
• W4313442029 hasRelatedWork W2170688882 @default.
• W4313442029 hasRelatedWork W2391750868 @default.
• W4313442029 hasRelatedWork W3006011994 @default.
• W4313442029 hasRelatedWork W4309949331 @default.

• next