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- W4313442282 abstract "This chapter describes the separation and determination of some neurotransmitters, represented by catecholamines, and some bioactive molecules, such as tranquilizers and antidepressants, using high performance capillary electrophoresis (HPCE). It describes the separation and determination by HPCE of other neurotransmitters besides catecholamines, and several bioactive molecules such as antidepressants, tranquilizers and hypnotics, which function through the central nervous system. Serotonin, a compound having an indole group, is biosynthesized from tryptophan and acts as a neurotransmitter through binding with a receptor and release to a synaptic cleft. Histamine is another biogenic amine which is distributed widely in mammalian tissues. Histamine plays an important role in allergy and inflammation. Benzodiazepines are representative of antidepressant and anticonvulsant drugs. Seven tricyclic antidepressants- protriptyline, desipramine, nortriptyline, nordoxepin, imipramine, amitriptyline and doxepin were separated by HPCE. Chiral separation of several barbitals was investigated with cyclodextrin-modified micellar CE." @default.
- W4313442282 created "2023-01-06" @default.
- W4313442282 creator A5009320265 @default.
- W4313442282 creator A5053293073 @default.
- W4313442282 date "2023-01-03" @default.
- W4313442282 modified "2023-10-16" @default.
- W4313442282 title "HPCE of catecholamines, bioactive molecules and other transmitters" @default.
- W4313442282 doi "https://doi.org/10.1201/9780429070280-14" @default.
- W4313442282 hasPublicationYear "2023" @default.
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