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- W4313442926 abstract "• Patients who do not respond to high-flow nasal cannula (HFNC) therapy may be at risk of delayed intubation and mortality. • We analyzed the medical records of 301 patients with acute hypoxemic respiratory failure who received HFNC therapy, and found that HFNC was unsuccessful in 22.9%. HFNC failure was associated with malignancy , C-reactive protein, and ROX index after HFNC; of those, the ROX index had an AUC of 0.652 and an optimal cut-off value of 6.66. • Our results suggest that medical staff at emergency departments should carefully monitor the ROX index of patients with acute respiratory failure undergoing HFNC. • We expect that a modified version of the ROX index can be used as a communicative tool among medical staff about the progress of patients with acute respiratory failure, which would be vital in preventing delayed intubation and reducing in-hospital mortality." @default.
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- W4313442926 date "2023-01-01" @default.
- W4313442926 modified "2023-10-18" @default.
- W4313442926 title "Factors associated with unsuccessful high-flow nasal cannula therapy in patients presenting to the emergency department for acute hypoxemic respiratory failure" @default.
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- W4313442926 doi "https://doi.org/10.1016/j.ienj.2022.101236" @default.
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