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- W4313443587 abstract "Each year, nearly 790,000 new cases of myocardial infarction (MI) are recorded in the United States, and 90,000 in France. Better knowledge of the modifiable risk factors for this cardiovascular disease remains a major public health issue. In this perspective, the aim of this systematic review and meta-analysis was to estimate the relationship between post-traumatic stress disorder (PTSD) and risk of subsequent myocardial infarction (MI). A systematic review using PRISMA (Preferred Reporting Items for Systematic reviews and Meta-Analysis) guidelines was performed by searching four bibliographic databases (PubMed/Medline, PsycINFO, Science Direct and Proquest Dissertations and Theses). A total of 14 articles were included. Nine of these included depression as a covariate. Among 13 studies (n = 848,903), the pooled HR for the magnitude of the relationship between PTSD and MI was 1.49 (95% CI 1.31–1.69) before adjustment for depression. The pooled HR estimate for the 9 depression-adjusted estimates (n = 814,441) was 1.32 (95% CI 1.12–1.56). Our results suggest that PTSD was associated with an increased risk of ischemic heart events and cardiovascular hospitalizations. Further research is still needed to identify in more precise terms the mediating factors involved in the direct association between PTSD and the subsequent occurrence of ischemic heart disease." @default.
- W4313443587 created "2023-01-06" @default.
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- W4313443587 date "2023-01-01" @default.
- W4313443587 modified "2023-10-05" @default.
- W4313443587 title "Relationship between post-traumatic stress disorder and subsequent myocardial infarction: A systematic review and meta-analysis" @default.
- W4313443587 doi "https://doi.org/10.1016/j.acvdsp.2022.10.301" @default.
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