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- W4313443818 abstract "Many cardiovascular risk factors proved their involvement in coronary atherosclerosis development. Some authors have shown that epicardial adipose tissue (EAT) can predict obstructive coronary artery disease (CAD). We aimed to find a correlation between common cardiovascular risk factors and EAT. This is a prospective descriptive study that included 100 consecutive patients admitted to the cardiology department of the hospital of the internal security forces of Marsa and having consulted between November 2020 and April 2021 for symptoms that required coronary angiography. The mean age was 58 ± 12 years, with a masculine predominance (sex ratio = 6.14). The mean values of mean end-diastolic EAT (MEDE) and mean end-systolic EAT (MESE) were 3.3 ± 8 mm and 5.1 ± 1.3 mm, respectively. MEDE and MESE were positively correlated with age (r = 0.485, P < 0.001; r = 0.397, P < 0.001, respectively). Smoking patients had higher MEDE (3.5 ± 0.9 vs. 3.1 ± 0.8, P = 0.016) while both, MEDE, and MESE, were significantly higher in diabetic patients (3.1 ± 0.8 vs. 3.6 ± 0.8, P = 0.008 and 4.8 ± 1.1 vs. 5.5 ± 1.4 p = 0.011, respectively), in dyslipidemic patients (2.8 ± 0.7 vs. 3.5 ± 0.8, P = 0.008 and 4.4 ± 1.1 vs. 5.3 ± 1.3, P = 0.025, respectively) and in patients with overweight/obesity (2.9 ± 0.8 vs. 3.5 ± 0.8, P = 0.018 and 4.6 ± 1.3 vs. 5.3 ± 1.3, P = 0.049, respectively). For the biological parameters, MESE was negatively correlated with high-density lipoprotein cholesterol (r = −0.227, P = 0.029) while a positive correlation was found between MEDE and hemoglobin A1c (r = 0.201, P = 0.048). On the other hand, MEDE and MESE had a positive correlation with fasting blood glucose (r = 0.227, P = 0.041). EAT and CAD share most of the cardiovascular risk factors, the fact that can improve the role of EAT in the cardiovascular risk assessment." @default.
- W4313443818 created "2023-01-06" @default.
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- W4313443818 date "2023-01-01" @default.
- W4313443818 modified "2023-09-26" @default.
- W4313443818 title "Epicardial adipose tissue and coronary artery disease: Do they share the same risk factors?" @default.
- W4313443818 doi "https://doi.org/10.1016/j.acvdsp.2022.10.136" @default.
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