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• W4313444468 endingPage "330" @default.
• W4313444468 startingPage "307" @default.
• W4313444468 abstract "The prevalence of heart failureHeart failure (HF) increases worldwide. Long-term maladaptive activation of the renin–angiotensin–aldosterone systemRenin-angiotensin-aldosterone system (RAAS) contributes to pathological left ventricular (LV) remodeling in the failing heart. Accordingly, RAASRenin-angiotensin-aldosterone system blockade induces reverse remodeling in HF patients. To date, number of large, randomized clinical trials have confirmed the efficacy of different RAASRenin-angiotensin-aldosterone system inhibitors in the management of HF with reduced LV ejection fraction (HFrEFHeart failure with reduced ejection fraction (HFrEF)). Therefore, actual HF guidelines recommend broad spectrum of RAASRenin-angiotensin-aldosterone system inhibitors including angiotensin-converting enzyme (ACE) inhibitors or angiotensin receptor blockersAngiotensin receptor blockers, and aldosteroneAldosterone antagonists to reduce morbidity and mortality of HFrEFHeart failure with reduced ejection fraction (HFrEF) patients. In addition, novel therapeutic approaches targeting the RAASRenin-angiotensin-aldosterone system such as dual angiotensin receptor and neprilysin inhibition (ARNiAngiotensin receptor and neprilysin inhibition (ARNI)) with sacubitril/valsartanSacubitril/valsartan still open new avenues for HF patients. In contrast to HFrEFHeart failure with reduced ejection fraction (HFrEF), RAASRenin-angiotensin-aldosterone system inhibitors have not been proven in HF with preserved LV ejection fraction (HFpEFHeart failure with preserved ejection fraction (HFpEF)). This review aimed to summarize the rationale for and our current knowledge of RAASRenin-angiotensin-aldosterone system inhibition in the clinical management of human HF." @default.
• W4313444468 created "2023-01-06" @default.
• W4313444468 creator A5003067202 @default.
• W4313444468 creator A5069772344 @default.
• W4313444468 date "2023-01-01" @default.
• W4313444468 modified "2023-10-18" @default.
• W4313444468 title "Renin–Angiotensin–Aldosterone System as an Old New Target in Heart Failure Therapy" @default.
• W4313444468 cites W1532191115 @default.
• W4313444468 cites W1596067399 @default.
• W4313444468 cites W1760228306 @default.
• W4313444468 cites W1951293753 @default.
• W4313444468 cites W1968949002 @default.
• W4313444468 cites W1985951474 @default.
• W4313444468 cites W1994079702 @default.
• W4313444468 cites W1997780004 @default.
• W4313444468 cites W2003563752 @default.
• W4313444468 cites W2006078326 @default.
• W4313444468 cites W2006910397 @default.
• W4313444468 cites W2007204386 @default.
• W4313444468 cites W2013860488 @default.
• W4313444468 cites W2021011733 @default.
• W4313444468 cites W2024689687 @default.
• W4313444468 cites W2028139057 @default.
• W4313444468 cites W2028273454 @default.
• W4313444468 cites W2030492405 @default.
• W4313444468 cites W2031187741 @default.
• W4313444468 cites W2032130572 @default.
• W4313444468 cites W2033969839 @default.
• W4313444468 cites W2050481558 @default.
• W4313444468 cites W2053071273 @default.
• W4313444468 cites W2053232655 @default.
• W4313444468 cites W2056893352 @default.
• W4313444468 cites W2058431890 @default.
• W4313444468 cites W2063402228 @default.
• W4313444468 cites W2068519950 @default.
• W4313444468 cites W2078395346 @default.
• W4313444468 cites W2083269406 @default.
• W4313444468 cites W2093885131 @default.
• W4313444468 cites W2097123331 @default.
• W4313444468 cites W2098418963 @default.
• W4313444468 cites W2098780362 @default.
• W4313444468 cites W2099372236 @default.
• W4313444468 cites W2100082183 @default.
• W4313444468 cites W2105138814 @default.
• W4313444468 cites W2108076556 @default.
• W4313444468 cites W2113698123 @default.
• W4313444468 cites W2116655536 @default.
• W4313444468 cites W2127254785 @default.
• W4313444468 cites W2129471761 @default.
• W4313444468 cites W2136167658 @default.
• W4313444468 cites W2152072062 @default.
• W4313444468 cites W2152094259 @default.
• W4313444468 cites W2159571720 @default.
• W4313444468 cites W2164705414 @default.
• W4313444468 cites W2164852092 @default.
• W4313444468 cites W2168453807 @default.
• W4313444468 cites W2168507847 @default.
• W4313444468 cites W2168907840 @default.
• W4313444468 cites W2171664972 @default.
• W4313444468 cites W2184697404 @default.
• W4313444468 cites W2224556300 @default.
• W4313444468 cites W2312388685 @default.
• W4313444468 cites W2323458614 @default.
• W4313444468 cites W2323639081 @default.
• W4313444468 cites W2326354230 @default.
• W4313444468 cites W2410085111 @default.
• W4313444468 cites W2469805673 @default.
• W4313444468 cites W2470304678 @default.
• W4313444468 cites W2551825405 @default.
• W4313444468 cites W2585382523 @default.
• W4313444468 cites W2595010755 @default.
• W4313444468 cites W2604463073 @default.
• W4313444468 cites W2608226954 @default.
• W4313444468 cites W2759147159 @default.
• W4313444468 cites W2770196824 @default.
• W4313444468 cites W2794823537 @default.
• W4313444468 cites W2797359325 @default.
• W4313444468 cites W2800798998 @default.
• W4313444468 cites W2805015756 @default.
• W4313444468 cites W2805115770 @default.
• W4313444468 cites W2883756867 @default.
• W4313444468 cites W2899841238 @default.
• W4313444468 cites W2913008332 @default.
• W4313444468 cites W2914497003 @default.
• W4313444468 cites W2947972779 @default.
• W4313444468 cites W2970357473 @default.
• W4313444468 cites W2970922997 @default.
• W4313444468 cites W2971294569 @default.
• W4313444468 cites W2995407169 @default.
• W4313444468 cites W3003299879 @default.
• W4313444468 cites W3004548118 @default.
• W4313444468 cites W3007643904 @default.
• W4313444468 cites W3009912996 @default.
• W4313444468 cites W3021063182 @default.
• W4313444468 cites W3034270991 @default.
• W4313444468 cites W3046806318 @default.
• W4313444468 cites W3048688534 @default.
• W4313444468 cites W3048778639 @default.

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