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- W4313444598 abstract "RA is a chronic and systemic autoimmune disease characterized by a significant role in disease development of external (environmental, diet, infection) and internal (genetic, microbiomeMicrobiome, hormonal) factors. Currently, the diagnosis of RA is mainly based on the presence and high titer of rheumatoid factor (RF) and anti-citrullinated protein antibodies (ACPAs) or anti-cyclic citrullinated peptide (anti-CCP) antibodies in the plasma. It is known that pathogenesis is associated with pathological processes in the mucous. One significant factor affecting disease development, course, treatment, and patient outcome is the microbiomeMicrobiome. Rheumatoid arthritisRheumatoid arthritis in aged people is significantly different due to intestinal agingAging as an aggravating factor, is more challenging to treat, and most often has an unfavorable outcome. Aged people have lower gutGut immunity and higher leaky gutGut syndrome, and the constant inflammatoryInflammatory changes in the aged gutGut are setting more fire on the RA of the elderly. In this chapter, we describe the EORAElderly Onset Rheumatoid Arthritis (EORA) microbiomeMicrobiome and mycobiome features, immune imbalances including data on clinical and genetic characteristics." @default.
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- W4313444598 date "2023-01-01" @default.
- W4313444598 modified "2023-10-18" @default.
- W4313444598 title "Gut Microbiota in Elderly Onset Rheumatoid Arthritis" @default.
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- W4313444598 doi "https://doi.org/10.1007/978-3-031-14023-5_9" @default.
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