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- W4313444686 abstract "The gutGut microbiomeGut microbiome playsMicrobiome an essential role in host health, mediated via its interaction with the immune system. Advancing ageAge is accompanied by alterations in gutGut microbiomeGut microbiome compositionMicrobiome and their functional features. In this chapter, we explore the impact of theseAge age-related microbiomeMicrobiome changes in contributing towards a state of immune dysfunction (immunesenescenceImmunesenescence) and low-grade basal inflammationInflammation (inflammagingInflammaging) in older adults. We propose that modulating the ageingAgeing gutGut microbiomeGut microbiome viaMicrobiome probioticProbiotics/prebioticPrebiotics supplementation, dietary interventions, fecal microbiota transplantation and therapeutic administration of microbiomeMicrobiome metabolites may serve as effective approaches to boost immune responses in older adults. However, future studies focused on developing a deeper understanding of the impact of aged microbiota on immunity is crucial for identifying novel microbiomeMicrobiome targets that can serve as anti-immunesenescenceImmunesenescence medicines, which is valuable for healthier ageingAgeing." @default.
- W4313444686 created "2023-01-06" @default.
- W4313444686 creator A5011620477 @default.
- W4313444686 creator A5028013575 @default.
- W4313444686 creator A5083267482 @default.
- W4313444686 date "2023-01-01" @default.
- W4313444686 modified "2023-10-18" @default.
- W4313444686 title "Ageing of the Gut Microbiome and Its Potential Contribution Towards Immunesenescence and Inflammaging" @default.
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