Matches in SemOpenAlex for { <https://semopenalex.org/work/W4313448448> ?p ?o ?g. }
Showing items 1 to 81 of
81
with 100 items per page.
- W4313448448 abstract "Abstract In this study, a powerful and rapid aqueous two-phase system (ATPS) method was used to extract polysaccharides from Codonopsis pilosula . The ATPS process was investigated with response surface methodology (RSM). At an ammonium sulfate concentration of 17%, ethanol concentration of 30%, and extraction temperature of 40 °C at pH 6, the total extraction yield of polysaccharides reached (31.57 ± 1.28) %. After separation and purification using a DEAE-52 cellulose column and dextran gel G-200, homogenized polysaccharide CPP 2–4 with a molecular weight of 3.9⋅10 4 kDa was obtained from the lower phase. The physicochemical properties and structural features confirmed that CPP 2–4 was an a-1,6-glucan. Activity studies showed that the IC 50 of CPP 2–4 for 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging was 0.105 mg/mL. Ferric reducing antioxidant power (FRAP) and 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) assays showed that CPP 2–4 had strong antioxidant activity in a dose-dependent manner. Furthermore, CPP 2–4 inhibited NO release in RAW264.7 cells induced by lipopolysaccharide (LPS), which indicated a certain anti-inflammatory effect. This study improved upon the low extraction rate of polysaccharides from Codonopsis pilosula and identified a glucan in Codonopsis pilosula for the first time. This study contributes to a better understanding of the composition and structure of polysaccharides from Codonopsis pilosula , provides a basis for the development of Codonopsis pilosula polysaccharides in food and health products, and provides data support for the medicine and food homology of Codonopsis pilosula ." @default.
- W4313448448 created "2023-01-06" @default.
- W4313448448 creator A5029700686 @default.
- W4313448448 creator A5031948825 @default.
- W4313448448 creator A5044318348 @default.
- W4313448448 creator A5053528603 @default.
- W4313448448 creator A5059215881 @default.
- W4313448448 creator A5063018750 @default.
- W4313448448 creator A5071807699 @default.
- W4313448448 creator A5076017095 @default.
- W4313448448 creator A5079304750 @default.
- W4313448448 date "2022-12-20" @default.
- W4313448448 modified "2023-10-12" @default.
- W4313448448 title "Extraction, structural characterization, and biological activities of a new glucan from Codonopsis pilosula" @default.
- W4313448448 cites W1435326582 @default.
- W4313448448 cites W1969382600 @default.
- W4313448448 cites W2032828829 @default.
- W4313448448 cites W2076665483 @default.
- W4313448448 cites W2134071616 @default.
- W4313448448 cites W2277121252 @default.
- W4313448448 cites W2517495532 @default.
- W4313448448 cites W2774982449 @default.
- W4313448448 cites W2795052661 @default.
- W4313448448 cites W2796764275 @default.
- W4313448448 cites W2883819385 @default.
- W4313448448 cites W2891088504 @default.
- W4313448448 cites W3088260783 @default.
- W4313448448 cites W3111618256 @default.
- W4313448448 doi "https://doi.org/10.21203/rs.3.rs-2368387/v1" @default.
- W4313448448 hasPublicationYear "2022" @default.
- W4313448448 type Work @default.
- W4313448448 citedByCount "0" @default.
- W4313448448 crossrefType "posted-content" @default.
- W4313448448 hasAuthorship W4313448448A5029700686 @default.
- W4313448448 hasAuthorship W4313448448A5031948825 @default.
- W4313448448 hasAuthorship W4313448448A5044318348 @default.
- W4313448448 hasAuthorship W4313448448A5053528603 @default.
- W4313448448 hasAuthorship W4313448448A5059215881 @default.
- W4313448448 hasAuthorship W4313448448A5063018750 @default.
- W4313448448 hasAuthorship W4313448448A5071807699 @default.
- W4313448448 hasAuthorship W4313448448A5076017095 @default.
- W4313448448 hasAuthorship W4313448448A5079304750 @default.
- W4313448448 hasBestOaLocation W43134484481 @default.
- W4313448448 hasConcept C100817775 @default.
- W4313448448 hasConcept C185592680 @default.
- W4313448448 hasConcept C2776123893 @default.
- W4313448448 hasConcept C2778004101 @default.
- W4313448448 hasConcept C2780161600 @default.
- W4313448448 hasConcept C2781031786 @default.
- W4313448448 hasConcept C2781401929 @default.
- W4313448448 hasConcept C31903555 @default.
- W4313448448 hasConcept C43617362 @default.
- W4313448448 hasConcept C4725764 @default.
- W4313448448 hasConcept C55493867 @default.
- W4313448448 hasConceptScore W4313448448C100817775 @default.
- W4313448448 hasConceptScore W4313448448C185592680 @default.
- W4313448448 hasConceptScore W4313448448C2776123893 @default.
- W4313448448 hasConceptScore W4313448448C2778004101 @default.
- W4313448448 hasConceptScore W4313448448C2780161600 @default.
- W4313448448 hasConceptScore W4313448448C2781031786 @default.
- W4313448448 hasConceptScore W4313448448C2781401929 @default.
- W4313448448 hasConceptScore W4313448448C31903555 @default.
- W4313448448 hasConceptScore W4313448448C43617362 @default.
- W4313448448 hasConceptScore W4313448448C4725764 @default.
- W4313448448 hasConceptScore W4313448448C55493867 @default.
- W4313448448 hasLocation W43134484481 @default.
- W4313448448 hasOpenAccess W4313448448 @default.
- W4313448448 hasPrimaryLocation W43134484481 @default.
- W4313448448 hasRelatedWork W1922309723 @default.
- W4313448448 hasRelatedWork W1990565430 @default.
- W4313448448 hasRelatedWork W2051006456 @default.
- W4313448448 hasRelatedWork W2352822135 @default.
- W4313448448 hasRelatedWork W2375833270 @default.
- W4313448448 hasRelatedWork W2391728758 @default.
- W4313448448 hasRelatedWork W2532574066 @default.
- W4313448448 hasRelatedWork W2800237421 @default.
- W4313448448 hasRelatedWork W2885756390 @default.
- W4313448448 hasRelatedWork W3136165283 @default.
- W4313448448 isParatext "false" @default.
- W4313448448 isRetracted "false" @default.
- W4313448448 workType "article" @default.