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- W4313448480 abstract "Three new dimeric polyketides, i.e., phaeochromycins I–K (1–3, respectively) and a known polyketide phaeochromycin F (4), were isolated from the culture broth of a saline Qinghai–Tibet Plateau permafrost soil-derived Streptomyces sp. 166#. The structures were determined by analyzing one-dimensional and two-dimensional NMR as well as HRESIMS data. Compounds 2 and 3 exhibited a selective antiproliferative activity against H1299 and HUCCT1 cell lines, exhibiting IC50 values ranging from 8.83 to 10.52 μM." @default.
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- W4313448480 date "2022-12-20" @default.
- W4313448480 modified "2023-10-16" @default.
- W4313448480 title "Phaeochromycins I–K, Three Methylene-Bridged Dimeric Polyketides from <i>Streptomyces</i> sp. 166#" @default.
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- W4313448480 doi "https://doi.org/10.1021/acsomega.2c07038" @default.
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