FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4313453800> ?p ?o ?g. }

• W4313453800 abstract "Abstract Background Bronchodilator responsiveness (BDR) using FEV 1 is often utilised to separate COPD patients from asthmatics, although it can be present in some COPD patients. With the advent of treatments with distal airway deposition, BDR in the small airways (SA) may be of value in the management of COPD. We aimed to identify the prevalence of BDR in the SA, utilizing maximal mid-expiratory flow (MMEF) as a measure of SA. We further evaluated the prevalence of BDR in MMEF with and without BDR in FEV 1 and its association with baseline demographics, including conventional airflow obstruction severity and smoking history. Methods Lung function data of ever-smoking COPD patients were retrospectively analysed. BDR was evaluated 20 min after administering 2.5 mg of salbutamol via jet nebulizer. Increase in percent change of ≥ 12% and absolute change of ≥ 200 ml was used to define a BDR in FEV 1 , whereas an increase percent change of MMEF ≥ 30% was used to define a BDR in MMEF. Patients were classified as one of three groups according to BDR levels: group 1 (BDR in MMEF and FEV 1 ), group 2 (BDR in MMEF alone) and group 3 (no BDR in either measure). Result BDR in MMEF was present in 59.2% of the patients. Of note, BDR in MMEF was present in all patients with BDR in FEV 1 (group 1) but also in 37.9% of the patients without BDR in FEV 1 (group 2). Patients in group 1 were younger than in groups 2 and 3. BMI was higher in group 1 than in group 3. Baseline FEV 1 % predicted and FVC % predicted were also higher in groups 1 and 2 than in group 3. Conclusion BDR in the SA (evaluated by MMEF) is common in COPD, and it is also feature seen in all patients with BDR in FEV 1 . Even in the absence of BDR in FEV 1 , BDR in MMEF is detected in some patients with COPD, potentially identifying a subgroup of patients who may benefit from different treatment strategies." @default.
• W4313453800 created "2023-01-06" @default.
• W4313453800 creator A5010056224 @default.
• W4313453800 creator A5031412055 @default.
• W4313453800 creator A5048830257 @default.
• W4313453800 creator A5066496623 @default.
• W4313453800 creator A5079649008 @default.
• W4313453800 date "2022-12-30" @default.
• W4313453800 modified "2023-10-14" @default.
• W4313453800 title "The prevalence of bronchodilator responsiveness of the small airway (using mid-maximal expiratory flow) in COPD - a retrospective study" @default.
• W4313453800 cites W107954301 @default.
• W4313453800 cites W1975696396 @default.
• W4313453800 cites W1981434879 @default.
• W4313453800 cites W1984788876 @default.
• W4313453800 cites W2029310315 @default.
• W4313453800 cites W2031234213 @default.
• W4313453800 cites W2038368394 @default.
• W4313453800 cites W2046448808 @default.
• W4313453800 cites W2099449365 @default.
• W4313453800 cites W2108356830 @default.
• W4313453800 cites W2109006492 @default.
• W4313453800 cites W2111563666 @default.
• W4313453800 cites W2124879124 @default.
• W4313453800 cites W2127624838 @default.
• W4313453800 cites W2128780995 @default.
• W4313453800 cites W2131988697 @default.
• W4313453800 cites W2142983489 @default.
• W4313453800 cites W2156131282 @default.
• W4313453800 cites W2157963054 @default.
• W4313453800 cites W2164158986 @default.
• W4313453800 cites W2169753088 @default.
• W4313453800 cites W2197553214 @default.
• W4313453800 cites W2253324331 @default.
• W4313453800 cites W2601617173 @default.
• W4313453800 cites W2924488943 @default.
• W4313453800 cites W2934087453 @default.
• W4313453800 cites W2950016883 @default.
• W4313453800 cites W2994597783 @default.
• W4313453800 cites W3040675612 @default.
• W4313453800 cites W3104187936 @default.
• W4313453800 cites W4226226313 @default.
• W4313453800 cites W4290382242 @default.
• W4313453800 cites W4299961969 @default.
• W4313453800 cites W4303192442 @default.
• W4313453800 doi "https://doi.org/10.1186/s12890-022-02235-0" @default.
• W4313453800 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36585669" @default.
• W4313453800 hasPublicationYear "2022" @default.
• W4313453800 type Work @default.
• W4313453800 citedByCount "0" @default.
• W4313453800 crossrefType "journal-article" @default.
• W4313453800 hasAuthorship W4313453800A5010056224 @default.
• W4313453800 hasAuthorship W4313453800A5031412055 @default.
• W4313453800 hasAuthorship W4313453800A5048830257 @default.
• W4313453800 hasAuthorship W4313453800A5066496623 @default.
• W4313453800 hasAuthorship W4313453800A5079649008 @default.
• W4313453800 hasBestOaLocation W43134538001 @default.
• W4313453800 hasConcept C105922876 @default.
• W4313453800 hasConcept C126322002 @default.
• W4313453800 hasConcept C141071460 @default.
• W4313453800 hasConcept C164705383 @default.
• W4313453800 hasConcept C2776042228 @default.
• W4313453800 hasConcept C2776780178 @default.
• W4313453800 hasConcept C2777394947 @default.
• W4313453800 hasConcept C2778333281 @default.
• W4313453800 hasConcept C2780352487 @default.
• W4313453800 hasConcept C2781018748 @default.
• W4313453800 hasConcept C2909548125 @default.
• W4313453800 hasConcept C2910285276 @default.
• W4313453800 hasConcept C42219234 @default.
• W4313453800 hasConcept C71924100 @default.
• W4313453800 hasConceptScore W4313453800C105922876 @default.
• W4313453800 hasConceptScore W4313453800C126322002 @default.
• W4313453800 hasConceptScore W4313453800C141071460 @default.
• W4313453800 hasConceptScore W4313453800C164705383 @default.
• W4313453800 hasConceptScore W4313453800C2776042228 @default.
• W4313453800 hasConceptScore W4313453800C2776780178 @default.
• W4313453800 hasConceptScore W4313453800C2777394947 @default.
• W4313453800 hasConceptScore W4313453800C2778333281 @default.
• W4313453800 hasConceptScore W4313453800C2780352487 @default.
• W4313453800 hasConceptScore W4313453800C2781018748 @default.
• W4313453800 hasConceptScore W4313453800C2909548125 @default.
• W4313453800 hasConceptScore W4313453800C2910285276 @default.
• W4313453800 hasConceptScore W4313453800C42219234 @default.
• W4313453800 hasConceptScore W4313453800C71924100 @default.
• W4313453800 hasFunder F4320330814 @default.
• W4313453800 hasIssue "1" @default.
• W4313453800 hasLocation W43134538001 @default.
• W4313453800 hasLocation W43134538002 @default.
• W4313453800 hasLocation W43134538003 @default.
• W4313453800 hasOpenAccess W4313453800 @default.
• W4313453800 hasPrimaryLocation W43134538001 @default.
• W4313453800 hasRelatedWork W2013725354 @default.
• W4313453800 hasRelatedWork W2049002202 @default.
• W4313453800 hasRelatedWork W21973157 @default.
• W4313453800 hasRelatedWork W2252156554 @default.
• W4313453800 hasRelatedWork W2461521344 @default.
• W4313453800 hasRelatedWork W2579016486 @default.
• W4313453800 hasRelatedWork W2742683051 @default.
• W4313453800 hasRelatedWork W3118828735 @default.
• W4313453800 hasRelatedWork W4226211385 @default.

• next