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- W4313455261 abstract "Quinoline-2-thiones valuable for synthetic and medicinal chemistry applications were obtained with excellent regioselectivity employing a deoxygenative C-H functionalization of readily available quinoline-N-oxides with thiourea upon activation with triflic anhydride. Unlike the current methods, this approach provides general access to diverse quinoline-2-thiones functionalized with groups of different electronic natures. Experimental simplicity and good to high yields are advantages of this protocol. Given the high reactivity of quinoline-2-thiones, this method provides an entry point for the synthesis of diverse organosulfur quinoline scaffolds." @default.
- W4313455261 created "2023-01-06" @default.
- W4313455261 creator A5048901737 @default.
- W4313455261 creator A5054273322 @default.
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- W4313455261 date "2023-01-03" @default.
- W4313455261 modified "2023-10-16" @default.
- W4313455261 title "Synthesis of Quinoline-2-thiones by Selective Deoxygenative C<i>–</i>H/C<i>–</i>S Functionalization of Quinoline <i>N</i>-Oxides with Thiourea" @default.
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- W4313455261 doi "https://doi.org/10.1021/acs.joc.2c02433" @default.
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