FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4313457068> ?p ?o ?g. }

• W4313457068 abstract "Abstract Everyday experience requires processing external signals from the world around us and internal information retrieved from memory. To do both, the brain must fluctuate between states that are optimized for external vs. internal attention. Here, we focus on the hippocampus as a region that may serve at the interface between these forms of attention, and ask how it switches between prioritizing sensory signals from the external world vs. internal signals related to memories and thoughts. Pharmacological, computational, and animal studies have identified input from the cholinergic basal forebrain as important for biasing the hippocampus towards processing external information, whereas complementary research suggests the dorsal attention network (DAN) may aid in allocating attentional resources towards accessing internal information. We therefore tested the hypothesis that the basal forebrain and DAN drive the hippocampus towards external and internal attention, respectively. We used data from 29 human participants (17 female) who completed 2 attention tasks during fMRI. One task (“memory-guided”) required proportionally more internal attention, and proportionally less external attention, than the other (“explicitly instructed”). We discovered that background functional connectivity between the basal forebrain and hippocampus was stronger during the explicitly instructed vs. memory-guided task. In contrast, DAN-hippocampus background connectivity was stronger during the memory-guided vs. explicitly instructed task. Finally, the strength of DAN-hippocampus background connectivity was correlated with performance on the memory-guided but not explicitly instructed task. Together, these results provide evidence that the basal forebrain and DAN may modulate the hippocampus to switch between external and internal attention. Significance Statement How does the brain balance the need to pay attention to internal thoughts and external sensations? We focused on the human hippocampus, a region that may serve at the interface between internal and external attention, and asked how its functional connectivity varies based on attentional states. The hippocampus was more strongly coupled with the cholinergic basal forebrain when attentional states were guided by the external world rather than retrieved memories. This pattern flipped for functional connectivity between the hippocampus and dorsal attention network, which was higher for attention tasks that were guided by memory rather than external cues. Together, these findings show that distinct networks in the brain may modulate the hippocampus to switch between external and internal attention." @default.
• W4313457068 created "2023-01-06" @default.
• W4313457068 creator A5058592040 @default.
• W4313457068 creator A5066819788 @default.
• W4313457068 date "2022-12-20" @default.
• W4313457068 modified "2023-10-16" @default.
• W4313457068 title "Switching between external and internal attention in hippocampal networks" @default.
• W4313457068 cites W1543878663 @default.
• W4313457068 cites W1563503562 @default.
• W4313457068 cites W1931790891 @default.
• W4313457068 cites W1967522734 @default.
• W4313457068 cites W1998268694 @default.
• W4313457068 cites W1999536394 @default.
• W4313457068 cites W2014550466 @default.
• W4313457068 cites W2016584175 @default.
• W4313457068 cites W2019370496 @default.
• W4313457068 cites W2037859048 @default.
• W4313457068 cites W2041128576 @default.
• W4313457068 cites W2042956033 @default.
• W4313457068 cites W2049191545 @default.
• W4313457068 cites W2052644075 @default.
• W4313457068 cites W2053696585 @default.
• W4313457068 cites W2062392933 @default.
• W4313457068 cites W2071881327 @default.
• W4313457068 cites W2078971310 @default.
• W4313457068 cites W2079082269 @default.
• W4313457068 cites W2084262425 @default.
• W4313457068 cites W2098732596 @default.
• W4313457068 cites W2100831964 @default.
• W4313457068 cites W2122896223 @default.
• W4313457068 cites W2124154193 @default.
• W4313457068 cites W2132774199 @default.
• W4313457068 cites W2140984633 @default.
• W4313457068 cites W2144380923 @default.
• W4313457068 cites W2152372327 @default.
• W4313457068 cites W2155100980 @default.
• W4313457068 cites W2162095066 @default.
• W4313457068 cites W2256689757 @default.
• W4313457068 cites W2262462128 @default.
• W4313457068 cites W2441854172 @default.
• W4313457068 cites W2594058977 @default.
• W4313457068 cites W2594708189 @default.
• W4313457068 cites W2753248866 @default.
• W4313457068 cites W2793174039 @default.
• W4313457068 cites W2804588657 @default.
• W4313457068 cites W2896767726 @default.
• W4313457068 cites W2911738947 @default.
• W4313457068 cites W2951618790 @default.
• W4313457068 cites W2953204335 @default.
• W4313457068 cites W2977883299 @default.
• W4313457068 cites W2997409898 @default.
• W4313457068 cites W3008601509 @default.
• W4313457068 cites W3015172918 @default.
• W4313457068 cites W3026917783 @default.
• W4313457068 cites W3043182589 @default.
• W4313457068 cites W3093130536 @default.
• W4313457068 cites W3096465824 @default.
• W4313457068 cites W3109766104 @default.
• W4313457068 cites W4296198255 @default.
• W4313457068 cites W4361304301 @default.
• W4313457068 cites W4367318278 @default.
• W4313457068 cites W4379741399 @default.
• W4313457068 doi "https://doi.org/10.1101/2022.12.20.521285" @default.
• W4313457068 hasPublicationYear "2022" @default.
• W4313457068 type Work @default.
• W4313457068 citedByCount "2" @default.
• W4313457068 countsByYear W43134570682023 @default.
• W4313457068 crossrefType "posted-content" @default.
• W4313457068 hasAuthorship W4313457068A5058592040 @default.
• W4313457068 hasAuthorship W4313457068A5066819788 @default.
• W4313457068 hasBestOaLocation W43134570681 @default.
• W4313457068 hasConcept C148762608 @default.
• W4313457068 hasConcept C15744967 @default.
• W4313457068 hasConcept C162324750 @default.
• W4313457068 hasConcept C169760540 @default.
• W4313457068 hasConcept C169900460 @default.
• W4313457068 hasConcept C180747234 @default.
• W4313457068 hasConcept C187736073 @default.
• W4313457068 hasConcept C21963081 @default.
• W4313457068 hasConcept C22885893 @default.
• W4313457068 hasConcept C2776287375 @default.
• W4313457068 hasConcept C2779226451 @default.
• W4313457068 hasConcept C2780451532 @default.
• W4313457068 hasConcept C2781161787 @default.
• W4313457068 hasConceptScore W4313457068C148762608 @default.
• W4313457068 hasConceptScore W4313457068C15744967 @default.
• W4313457068 hasConceptScore W4313457068C162324750 @default.
• W4313457068 hasConceptScore W4313457068C169760540 @default.
• W4313457068 hasConceptScore W4313457068C169900460 @default.
• W4313457068 hasConceptScore W4313457068C180747234 @default.
• W4313457068 hasConceptScore W4313457068C187736073 @default.
• W4313457068 hasConceptScore W4313457068C21963081 @default.
• W4313457068 hasConceptScore W4313457068C22885893 @default.
• W4313457068 hasConceptScore W4313457068C2776287375 @default.
• W4313457068 hasConceptScore W4313457068C2779226451 @default.
• W4313457068 hasConceptScore W4313457068C2780451532 @default.
• W4313457068 hasConceptScore W4313457068C2781161787 @default.
• W4313457068 hasLocation W43134570681 @default.
• W4313457068 hasOpenAccess W4313457068 @default.
• W4313457068 hasPrimaryLocation W43134570681 @default.

• next