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• W4313463313 endingPage "115216" @default.
• W4313463313 startingPage "115216" @default.
• W4313463313 abstract "The present study was aimed to assess infant safety associated with the presence of persistent organochlorine pesticides (OCPs) in breast milk, a possible route of transfer of endocrine–disrupting chemicals to newborns in North India. Colostrum and breast milk samples (n = 130) were collected at different stages of lactation. Pesticides analysis was performed using gas chromatography mass spectrometry (GC–MS). We observed that of all the samples analysed, OCPs concentration was higher in breast milk than in colostrum, suggesting pesticides contamination increases over lactation period. As far as OCPs are concerned, dieldrin [1196.64 ± 673.75 ng/g lipid weight (lw)], and β-HCH [1107.78 ± 1301.72 ng/g lw], were the predominant OCPs, followed by aldrin [977.09 ± 707.69 ng/g lw], α-HCH [948.04 ± 476.65 ng/g lw] and 1,1′-(2,2-Dichloroethene-1,1-diyl)bis(4-chlorobenzene) (p,p’DDE) [790.11 ± 399.35 ng/g lw]. The association between OCPs levels and women dietary habits were also explored, and all the OCPs were grouped and compared to each other by consumption level of fish, meat, sea foods, eggs, and dairy products. We found that women consuming non vegetarian food, like fish and meat, were exposed 3.5 times more to OCPs than women consuming vegetarian food. In addition, we also observed that factors like mother's age was positively (<0.005 - <0.001) correlated while gestational age and infant birth weight were negatively (<0.005) associated with the levels of OCPs in colostrum and breast milk, respectively. Unfortunately, neither any standards nor guidelines are available for the use of pesticides, therefore, it is suggested that careless use of OCPs should be checked and suitable remedial measures be taken to decrease human contamination. Moreover, further studies are warranted to elucidate relationship between pesticide residues in breast milk and the maternal and child health." @default.
• W4313463313 created "2023-01-06" @default.
• W4313463313 creator A5000378628 @default.
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• W4313463313 date "2023-03-01" @default.
• W4313463313 modified "2023-09-30" @default.
• W4313463313 title "Assessment of endocrine disrupting chemicals in breast milk: Association with dietary habits and duration of lactation" @default.
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• W4313463313 doi "https://doi.org/10.1016/j.envres.2023.115216" @default.
• W4313463313 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36608766" @default.
• W4313463313 hasPublicationYear "2023" @default.
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