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- W4313463380 abstract "This chapter discusses the gene drive systems and describe pioneering applications to control mosquito populations and prevent parasite transmission. Non-target effects are those that impact any organism other than the designated target and the potential for these is one of the most common concerns expressed about gene drive systems for malaria control. Population modification refers to a class of disease-control strategies that use genetic technologies to make vectors incapable of transmitting pathogens. The approaches discussed here involve the introduction of exogenous genes or modification of endogenous genes in populations of mosquitoes to confer resistance to the malaria parasites with the expectation that this will result in decreased transmission of the pathogen. The chapter focuses on the Anopheline vectors of human malaria, but what is being done with these and other species is expected to inform future design features for vector strains for malaria control." @default.
- W4313463380 created "2023-01-06" @default.
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- W4313463380 date "2023-01-03" @default.
- W4313463380 modified "2023-10-02" @default.
- W4313463380 title "Gene Drive Applications for Malaria Control" @default.
- W4313463380 doi "https://doi.org/10.1201/9781003308775-6" @default.
- W4313463380 hasPublicationYear "2023" @default.
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