Matches in SemOpenAlex for { <https://semopenalex.org/work/W4313471627> ?p ?o ?g. }
Showing items 1 to 98 of
98
with 100 items per page.
- W4313471627 endingPage "297" @default.
- W4313471627 startingPage "297" @default.
- W4313471627 abstract "Background and aim: Pancreato-biliary patients who undergo endoscopic procedures have high potential risk of delirium. Although benzodiazepine has traditionally been used to treat insomnia, this drug might increase delirium. Lemborexant may be useful for patients with insomnia, without worsening delirium, although there is no evidence for high-risk patients with pancreato-biliary disease. The aim of this pilot study was to evaluate the safety and efficacy of lemborexant for insomnia and the frequency of delirium after endoscopic procedures under deep sedation in patients with pancreato-biliary disease. Method: This retrospective study included consecutive patients who were administered lemborexant after endoscopic procedures for pancreato-biliary disease between September 2020 and June 2022. The primary outcome of this study was evaluation of the safety and efficacy of lemborexant for insomnia. Frequency of delirium was the secondary outcome. Result: In total, 64 patients who had the complication of insomnia after an endoscopic procedure were included in the study. Risk factors for delirium were advanced age (n = 36, 56.3%), dementia (n = 10, 15.6%), and regular alcohol use (n = 13, 20.3%), as well as the sedatives midazolam and pentazocine that were administered to all patients at the time of the endoscopic procedure. Successful asleep was achieved by 61/64 patients (95.3%). No fall event was observed during the night following the procedure in any patient. However, mild consciousness transformation was observed in one patient. Conclusions: In conclusion, lemborexant use may be effective and safe for use after endoscopic procedures in pancreato-biliary patients, without increasing the risk of delirium." @default.
- W4313471627 created "2023-01-06" @default.
- W4313471627 creator A5004891704 @default.
- W4313471627 creator A5016886341 @default.
- W4313471627 creator A5028671386 @default.
- W4313471627 creator A5046373191 @default.
- W4313471627 creator A5058900484 @default.
- W4313471627 creator A5063339600 @default.
- W4313471627 creator A5064285556 @default.
- W4313471627 creator A5064853411 @default.
- W4313471627 creator A5067557301 @default.
- W4313471627 creator A5086172496 @default.
- W4313471627 creator A5087815019 @default.
- W4313471627 date "2022-12-30" @default.
- W4313471627 modified "2023-09-26" @default.
- W4313471627 title "Can Lemborexant for Insomnia Prevent Delirium in High-Risk Patients with Pancreato-Biliary Disease after Endoscopic Procedures under Deep Sedation?" @default.
- W4313471627 cites W1968604707 @default.
- W4313471627 cites W1973798824 @default.
- W4313471627 cites W1995955106 @default.
- W4313471627 cites W2040415650 @default.
- W4313471627 cites W2047362129 @default.
- W4313471627 cites W2076668534 @default.
- W4313471627 cites W2125528441 @default.
- W4313471627 cites W2138141660 @default.
- W4313471627 cites W2141710162 @default.
- W4313471627 cites W2159048179 @default.
- W4313471627 cites W2294229758 @default.
- W4313471627 cites W2342263513 @default.
- W4313471627 cites W2539992626 @default.
- W4313471627 cites W2741472643 @default.
- W4313471627 cites W2884644339 @default.
- W4313471627 cites W2885896746 @default.
- W4313471627 cites W2926598623 @default.
- W4313471627 cites W2965638497 @default.
- W4313471627 cites W2998259693 @default.
- W4313471627 cites W3015144627 @default.
- W4313471627 cites W3015449951 @default.
- W4313471627 cites W3044393741 @default.
- W4313471627 cites W4210552118 @default.
- W4313471627 cites W4224315133 @default.
- W4313471627 cites W4247665917 @default.
- W4313471627 cites W4284957967 @default.
- W4313471627 doi "https://doi.org/10.3390/jcm12010297" @default.
- W4313471627 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36615100" @default.
- W4313471627 hasPublicationYear "2022" @default.
- W4313471627 type Work @default.
- W4313471627 citedByCount "0" @default.
- W4313471627 crossrefType "journal-article" @default.
- W4313471627 hasAuthorship W4313471627A5004891704 @default.
- W4313471627 hasAuthorship W4313471627A5016886341 @default.
- W4313471627 hasAuthorship W4313471627A5028671386 @default.
- W4313471627 hasAuthorship W4313471627A5046373191 @default.
- W4313471627 hasAuthorship W4313471627A5058900484 @default.
- W4313471627 hasAuthorship W4313471627A5063339600 @default.
- W4313471627 hasAuthorship W4313471627A5064285556 @default.
- W4313471627 hasAuthorship W4313471627A5064853411 @default.
- W4313471627 hasAuthorship W4313471627A5067557301 @default.
- W4313471627 hasAuthorship W4313471627A5086172496 @default.
- W4313471627 hasAuthorship W4313471627A5087815019 @default.
- W4313471627 hasBestOaLocation W43134716271 @default.
- W4313471627 hasConcept C141071460 @default.
- W4313471627 hasConcept C167135981 @default.
- W4313471627 hasConcept C177713679 @default.
- W4313471627 hasConcept C2776814716 @default.
- W4313471627 hasConcept C2778000748 @default.
- W4313471627 hasConcept C2779753318 @default.
- W4313471627 hasConcept C42219234 @default.
- W4313471627 hasConcept C71924100 @default.
- W4313471627 hasConceptScore W4313471627C141071460 @default.
- W4313471627 hasConceptScore W4313471627C167135981 @default.
- W4313471627 hasConceptScore W4313471627C177713679 @default.
- W4313471627 hasConceptScore W4313471627C2776814716 @default.
- W4313471627 hasConceptScore W4313471627C2778000748 @default.
- W4313471627 hasConceptScore W4313471627C2779753318 @default.
- W4313471627 hasConceptScore W4313471627C42219234 @default.
- W4313471627 hasConceptScore W4313471627C71924100 @default.
- W4313471627 hasIssue "1" @default.
- W4313471627 hasLocation W43134716271 @default.
- W4313471627 hasLocation W43134716272 @default.
- W4313471627 hasLocation W43134716273 @default.
- W4313471627 hasOpenAccess W4313471627 @default.
- W4313471627 hasPrimaryLocation W43134716271 @default.
- W4313471627 hasRelatedWork W2045978731 @default.
- W4313471627 hasRelatedWork W2056192879 @default.
- W4313471627 hasRelatedWork W2067315608 @default.
- W4313471627 hasRelatedWork W2090840481 @default.
- W4313471627 hasRelatedWork W2110127181 @default.
- W4313471627 hasRelatedWork W2115823456 @default.
- W4313471627 hasRelatedWork W2134102731 @default.
- W4313471627 hasRelatedWork W2350082559 @default.
- W4313471627 hasRelatedWork W2411727155 @default.
- W4313471627 hasRelatedWork W2887406189 @default.
- W4313471627 hasVolume "12" @default.
- W4313471627 isParatext "false" @default.
- W4313471627 isRetracted "false" @default.
- W4313471627 workType "article" @default.