Matches in SemOpenAlex for { <https://semopenalex.org/work/W4313472002> ?p ?o ?g. }
- W4313472002 endingPage "83" @default.
- W4313472002 startingPage "83" @default.
- W4313472002 abstract "Ceramide (Cer) plays an important role in skin barrier functions in the stratum corneum (SC). The ingestion of food-derived glucosylceramides (GlcCer) attenuates transepidermal water loss (TEWL). However, the moisturizing effects of single molecules of GlcCer and Cer remain unclear. Therefore, we herein purified 13 GlcCer and 6 Cer, including elasticamide, which has the same structure as human Cer[AP], from rice and compared their epidermal moisturizing effects in a reconstructed human epidermal keratinization model. The results obtained showed that 10 µM of 5 GlcCer[d18:2] with a 4E,8Z sphingadienine and C18 to C26 fatty acids and 10 µg/mL of 3 Cer with C23 or C24 fatty acids significantly reduced TEWL. The moisturizing effects of these GlcCer were dependent on the length of fatty acids. Furthermore, 10 µg/mL of elasticamide increased the SC Cer contents by promoting the expression of GlcCer synthase. Electron microscopic observations revealed that 1 µM of GlcCer[d18:2(4E,8Z)/26:0] increased the number of keratohyalin granules and desmosomes. Immunostaining and Western blotting indicated that 1 µM of GlcCer[d18:2(4E,8Z)/26:0] up-regulated the expression of filaggrin and corneodesmosin, which contribute to epidermal hydration. This comparative study on epidermal moisturization by GlcCer and Cer isolated from rice revealed differences in their hydration mechanisms." @default.
- W4313472002 created "2023-01-06" @default.
- W4313472002 creator A5031585366 @default.
- W4313472002 creator A5035839283 @default.
- W4313472002 creator A5036719255 @default.
- W4313472002 creator A5084887244 @default.
- W4313472002 creator A5085041072 @default.
- W4313472002 creator A5087445208 @default.
- W4313472002 date "2022-12-21" @default.
- W4313472002 modified "2023-09-25" @default.
- W4313472002 title "Comparative Study on Epidermal Moisturizing Effects and Hydration Mechanisms of Rice-Derived Glucosylceramides and Ceramides" @default.
- W4313472002 cites W1481912870 @default.
- W4313472002 cites W173468590 @default.
- W4313472002 cites W1822696893 @default.
- W4313472002 cites W1975512501 @default.
- W4313472002 cites W1988469304 @default.
- W4313472002 cites W1989832969 @default.
- W4313472002 cites W2001983193 @default.
- W4313472002 cites W2024710730 @default.
- W4313472002 cites W2026275425 @default.
- W4313472002 cites W2027386197 @default.
- W4313472002 cites W2041922728 @default.
- W4313472002 cites W2054083814 @default.
- W4313472002 cites W2054180944 @default.
- W4313472002 cites W2067017343 @default.
- W4313472002 cites W2076023278 @default.
- W4313472002 cites W2078228321 @default.
- W4313472002 cites W2082846747 @default.
- W4313472002 cites W2082956701 @default.
- W4313472002 cites W2101740966 @default.
- W4313472002 cites W2111253973 @default.
- W4313472002 cites W2116758775 @default.
- W4313472002 cites W2121684289 @default.
- W4313472002 cites W2129016936 @default.
- W4313472002 cites W2129179796 @default.
- W4313472002 cites W2130901513 @default.
- W4313472002 cites W2133242794 @default.
- W4313472002 cites W2144410604 @default.
- W4313472002 cites W2151970579 @default.
- W4313472002 cites W2155762643 @default.
- W4313472002 cites W2169851453 @default.
- W4313472002 cites W2295976626 @default.
- W4313472002 cites W2327022335 @default.
- W4313472002 cites W2375675880 @default.
- W4313472002 cites W2526949057 @default.
- W4313472002 cites W2576004968 @default.
- W4313472002 cites W2752310987 @default.
- W4313472002 cites W2896175173 @default.
- W4313472002 cites W2897473280 @default.
- W4313472002 cites W2970469297 @default.
- W4313472002 cites W3120428759 @default.
- W4313472002 cites W3134518450 @default.
- W4313472002 cites W3137179729 @default.
- W4313472002 cites W3196550386 @default.
- W4313472002 cites W3204365977 @default.
- W4313472002 cites W3210342668 @default.
- W4313472002 cites W4281961679 @default.
- W4313472002 cites W4292542418 @default.
- W4313472002 doi "https://doi.org/10.3390/ijms24010083" @default.
- W4313472002 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36613524" @default.
- W4313472002 hasPublicationYear "2022" @default.
- W4313472002 type Work @default.
- W4313472002 citedByCount "0" @default.
- W4313472002 crossrefType "journal-article" @default.
- W4313472002 hasAuthorship W4313472002A5031585366 @default.
- W4313472002 hasAuthorship W4313472002A5035839283 @default.
- W4313472002 hasAuthorship W4313472002A5036719255 @default.
- W4313472002 hasAuthorship W4313472002A5084887244 @default.
- W4313472002 hasAuthorship W4313472002A5085041072 @default.
- W4313472002 hasAuthorship W4313472002A5087445208 @default.
- W4313472002 hasBestOaLocation W43134720021 @default.
- W4313472002 hasConcept C179927520 @default.
- W4313472002 hasConcept C185592680 @default.
- W4313472002 hasConcept C190283241 @default.
- W4313472002 hasConcept C190684412 @default.
- W4313472002 hasConcept C203014093 @default.
- W4313472002 hasConcept C2777851122 @default.
- W4313472002 hasConcept C2778329239 @default.
- W4313472002 hasConcept C2778370115 @default.
- W4313472002 hasConcept C54355233 @default.
- W4313472002 hasConcept C55493867 @default.
- W4313472002 hasConcept C61705674 @default.
- W4313472002 hasConcept C86803240 @default.
- W4313472002 hasConcept C95150158 @default.
- W4313472002 hasConceptScore W4313472002C179927520 @default.
- W4313472002 hasConceptScore W4313472002C185592680 @default.
- W4313472002 hasConceptScore W4313472002C190283241 @default.
- W4313472002 hasConceptScore W4313472002C190684412 @default.
- W4313472002 hasConceptScore W4313472002C203014093 @default.
- W4313472002 hasConceptScore W4313472002C2777851122 @default.
- W4313472002 hasConceptScore W4313472002C2778329239 @default.
- W4313472002 hasConceptScore W4313472002C2778370115 @default.
- W4313472002 hasConceptScore W4313472002C54355233 @default.
- W4313472002 hasConceptScore W4313472002C55493867 @default.
- W4313472002 hasConceptScore W4313472002C61705674 @default.
- W4313472002 hasConceptScore W4313472002C86803240 @default.
- W4313472002 hasConceptScore W4313472002C95150158 @default.
- W4313472002 hasIssue "1" @default.