FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4313473416> ?p ?o ?g. }

• W4313473416 endingPage "91" @default.
• W4313473416 startingPage "91" @default.
• W4313473416 abstract "Epilobium species are used in Romanian folk medicine as tinctures, tea, or tablets for ameliorating the symptoms of benign prostate hyperplasia (BPH), but scientific-based evidence is scarce for this species or other endemic plants of the same genus. Therefore, the aims of this research were to evaluate the phytochemical profile of five endemic Epilobium species (E. hirsutum L., E. parviflorum Schreb., E. palustre L. E. dodonaei Vill., and E. angustifolium L.) and to assess their in vitro biological activity. For enhanced recovery of polyphenols, a D-optimal experimental plan was developed using Modde software and the optimal working conditions were ultra-turrax-assisted extraction, for 8 min, with 30% ethanol in water. The optimized extracts were obtained from various plant parts and were further characterized by LC-MS analysis, with the major compound being oenothein B. All extracts demonstrated good antioxidant activity, evaluated by DPPH and TEAC assays. The most prominent antimicrobial potency of optimized extracts was displayed against Bacillus cereus, while against Gram-(+) bacteria, a moderate efficacy was observed. Furthermore, anti-cancer, anti-inflammatory, and antioxidant potential were assessed on normal fibroblasts and prostate carcinoma cell lines. From the evaluated optimized extracts, E. angustifolium aerial parts had the highest selectivity toward killing cancerous cells, followed by E. hirsutum aerial parts extract. For the antioxidant effect, E. hirsutum leaves and E. hirstum aerial parts extracts displayed the highest potency, decreasing ROS at the level observed for the positive control. The highest anti-inflammatory potential, based on the IL-6 and IL-8 levels, was displayed by E. dodonaei aerial parts and E. angustifolium leaves extracts. In conclusion, all five endemic species of Epilobium harvested from Romanian flora possess a diverse phytochemical composition, which supports complex biological activities." @default.
• W4313473416 created "2023-01-06" @default.
• W4313473416 creator A5001751512 @default.
• W4313473416 creator A5020382198 @default.
• W4313473416 creator A5035200518 @default.
• W4313473416 creator A5040484891 @default.
• W4313473416 creator A5045299338 @default.
• W4313473416 creator A5045953399 @default.
• W4313473416 creator A5047157583 @default.
• W4313473416 creator A5047935143 @default.
• W4313473416 creator A5050241795 @default.
• W4313473416 creator A5065281970 @default.
• W4313473416 creator A5068349878 @default.
• W4313473416 date "2022-12-30" @default.
• W4313473416 modified "2023-10-18" @default.
• W4313473416 title "Epilobium Species: From Optimization of the Extraction Process to Evaluation of Biological Properties" @default.
• W4313473416 cites W1858576343 @default.
• W4313473416 cites W1979177362 @default.
• W4313473416 cites W1990152563 @default.
• W4313473416 cites W2003484224 @default.
• W4313473416 cites W2008736119 @default.
• W4313473416 cites W2022728053 @default.
• W4313473416 cites W2030629629 @default.
• W4313473416 cites W2032088440 @default.
• W4313473416 cites W2042166290 @default.
• W4313473416 cites W2071480265 @default.
• W4313473416 cites W2077474987 @default.
• W4313473416 cites W2077848329 @default.
• W4313473416 cites W2082124233 @default.
• W4313473416 cites W2085273152 @default.
• W4313473416 cites W2099517776 @default.
• W4313473416 cites W2105848263 @default.
• W4313473416 cites W2118272651 @default.
• W4313473416 cites W2549101019 @default.
• W4313473416 cites W2609624404 @default.
• W4313473416 cites W2790448310 @default.
• W4313473416 cites W2790931515 @default.
• W4313473416 cites W2810408837 @default.
• W4313473416 cites W2883585783 @default.
• W4313473416 cites W2898978334 @default.
• W4313473416 cites W2935646924 @default.
• W4313473416 cites W2940198494 @default.
• W4313473416 cites W2962760377 @default.
• W4313473416 cites W2979834681 @default.
• W4313473416 cites W2982689983 @default.
• W4313473416 cites W3008141455 @default.
• W4313473416 cites W3023104806 @default.
• W4313473416 cites W3023906400 @default.
• W4313473416 cites W3034124566 @default.
• W4313473416 cites W3045161616 @default.
• W4313473416 cites W3083659507 @default.
• W4313473416 cites W3096705036 @default.
• W4313473416 cites W3107948211 @default.
• W4313473416 cites W3115167472 @default.
• W4313473416 cites W3115356078 @default.
• W4313473416 cites W3118520446 @default.
• W4313473416 cites W3138141706 @default.
• W4313473416 cites W3152777588 @default.
• W4313473416 cites W3153979335 @default.
• W4313473416 cites W3173008452 @default.
• W4313473416 cites W3178907480 @default.
• W4313473416 cites W3197021175 @default.
• W4313473416 cites W3205236281 @default.
• W4313473416 cites W3205465123 @default.
• W4313473416 cites W3205950429 @default.
• W4313473416 cites W3215770225 @default.
• W4313473416 cites W4210798423 @default.
• W4313473416 cites W4220839915 @default.
• W4313473416 cites W4220960384 @default.
• W4313473416 cites W4281630311 @default.
• W4313473416 cites W4296741941 @default.
• W4313473416 doi "https://doi.org/10.3390/antiox12010091" @default.
• W4313473416 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36670952" @default.
• W4313473416 hasPublicationYear "2022" @default.
• W4313473416 type Work @default.
• W4313473416 citedByCount "2" @default.
• W4313473416 countsByYear W43134734162023 @default.
• W4313473416 crossrefType "journal-article" @default.
• W4313473416 hasAuthorship W4313473416A5001751512 @default.
• W4313473416 hasAuthorship W4313473416A5020382198 @default.
• W4313473416 hasAuthorship W4313473416A5035200518 @default.
• W4313473416 hasAuthorship W4313473416A5040484891 @default.
• W4313473416 hasAuthorship W4313473416A5045299338 @default.
• W4313473416 hasAuthorship W4313473416A5045953399 @default.
• W4313473416 hasAuthorship W4313473416A5047157583 @default.
• W4313473416 hasAuthorship W4313473416A5047935143 @default.
• W4313473416 hasAuthorship W4313473416A5050241795 @default.
• W4313473416 hasAuthorship W4313473416A5065281970 @default.
• W4313473416 hasAuthorship W4313473416A5068349878 @default.
• W4313473416 hasBestOaLocation W43134734161 @default.
• W4313473416 hasConcept C185592680 @default.
• W4313473416 hasConcept C195475562 @default.
• W4313473416 hasConcept C202751555 @default.
• W4313473416 hasConcept C2778004101 @default.
• W4313473416 hasConcept C2779510327 @default.
• W4313473416 hasConcept C2781401929 @default.
• W4313473416 hasConcept C4937899 @default.
• W4313473416 hasConcept C55493867 @default.

• next