FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4313477130> ?p ?o ?g. }

• W4313477130 abstract "Cardiac sarcoidosis (CS) is an underappreciated diagnosis in healthy patients presenting with recurrent syncope. This may be particularly limited in patients who do not meet common epidemiology and manifestations of sarcoidosis, which are typically African American women and pulmonary, respectively. In our case, we have a previously healthy middle-aged Caucasian American male who presented with recurrent syncope for one week. Initial electrocardiogram showed a right bundle branch block with a normal P-R interval. A few days into the admission, the patient suffered another episode of syncope precipitated by micturition, and repeat electrocardiogram revealed evolution to complete atrioventricular block, necessitating emergent placement of a temporary permanent pacemaker. Transthoracic echocardiogram showed preserved left ventricular ejection fraction of 55%-60% with normal heart valves. Chest computerized tomography revealed few pulmonary nodules, prompting a weak concern for infiltrative disease, e.g., sarcoidosis. To evaluate for possible cardiac structural abnormalities, a cardiac magnetic resonance imaging (MRI) study was considered but precluded by the presence of MRI-incompatible temporary pacemaker. Despite low suspicion, a fluorodeoxyglucose-positron emission tomography was obtained which unexpectedly revealed hypermetabolic lymph nodes in the perihilar, supraclavicular, and mediastinal regions as well as an area along the interventricular septum, consistent with atrioventricular (AV) conduction pathways. As the patient met major criteria for CS per Japanese Circulation Society guidelines, a tentative diagnosis was made, and a Biotronik single-chamber implantable cardiac defibrillator was ultimately placed. On outpatient follow-up, endobronchial ultrasound-guided fine-needle biopsy of perihilar lymph nodes revealed only rare epithelioid histiocytes, rare alveolar macrophages, and benign bronchial cells, consistent with benign nodal tissue. Further attempts for histological confirmation were aborted due to profound calcification and location of affected lymph nodes. A decision was made to defer further biopsy, including the gold standard of diagnosis endomyocardial biopsy, due to the risks outweighing the benefits. He initiated medical therapy with prednisone and mycophenolate, as well as trimethoprim-sulfamethoxazole for Pneumocystis prophylaxis. Unlike general sarcoidosis, which is often considered a benign systemic disease, CS has high potential for severe complications including arrhythmia, systolic heart failure, and sudden cardiac death. In general, males carry a higher risk of CS than females, especially those who are of African American descent as they carry a higher incidence of nonspecific sarcoidosis. Expectations related to our patient's demographic initially delayed diagnostic workup for infiltrative disease, primarily focusing on intracranial, orthostatic, and infectious causes. This case report serves to inform clinicians on early manifestations of CS, raise awareness of its incidence in unexpected demographics, and encourage them to consider infiltrative diseases when presented with patients of similar symptoms." @default.
• W4313477130 created "2023-01-06" @default.
• W4313477130 creator A5021343654 @default.
• W4313477130 creator A5082212780 @default.
• W4313477130 date "2023-01-04" @default.
• W4313477130 modified "2023-10-09" @default.
• W4313477130 title "Unexpected Case of Cardiac Sarcoidosis in a Caucasian Male" @default.
• W4313477130 cites W1540159173 @default.
• W4313477130 cites W2010909136 @default.
• W4313477130 cites W2026246759 @default.
• W4313477130 cites W2108790093 @default.
• W4313477130 cites W2163348196 @default.
• W4313477130 cites W2179009410 @default.
• W4313477130 cites W2191422580 @default.
• W4313477130 cites W2478646177 @default.
• W4313477130 cites W2508716736 @default.
• W4313477130 cites W2509449175 @default.
• W4313477130 cites W2618459605 @default.
• W4313477130 cites W2886047780 @default.
• W4313477130 cites W2888113997 @default.
• W4313477130 cites W2900277959 @default.
• W4313477130 cites W2942911605 @default.
• W4313477130 cites W2964101299 @default.
• W4313477130 cites W3091154226 @default.
• W4313477130 cites W3135851118 @default.
• W4313477130 cites W4233754515 @default.
• W4313477130 cites W4283696083 @default.
• W4313477130 doi "https://doi.org/10.7759/cureus.33353" @default.
• W4313477130 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36751252" @default.
• W4313477130 hasPublicationYear "2023" @default.
• W4313477130 type Work @default.
• W4313477130 citedByCount "0" @default.
• W4313477130 crossrefType "journal-article" @default.
• W4313477130 hasAuthorship W4313477130A5021343654 @default.
• W4313477130 hasAuthorship W4313477130A5082212780 @default.
• W4313477130 hasBestOaLocation W43134771301 @default.
• W4313477130 hasConcept C118552586 @default.
• W4313477130 hasConcept C126322002 @default.
• W4313477130 hasConcept C126838900 @default.
• W4313477130 hasConcept C143409427 @default.
• W4313477130 hasConcept C164705383 @default.
• W4313477130 hasConcept C2776008845 @default.
• W4313477130 hasConcept C2777682441 @default.
• W4313477130 hasConcept C2778557577 @default.
• W4313477130 hasConcept C2778921608 @default.
• W4313477130 hasConcept C2779740085 @default.
• W4313477130 hasConcept C2780724011 @default.
• W4313477130 hasConcept C2781301800 @default.
• W4313477130 hasConcept C71924100 @default.
• W4313477130 hasConceptScore W4313477130C118552586 @default.
• W4313477130 hasConceptScore W4313477130C126322002 @default.
• W4313477130 hasConceptScore W4313477130C126838900 @default.
• W4313477130 hasConceptScore W4313477130C143409427 @default.
• W4313477130 hasConceptScore W4313477130C164705383 @default.
• W4313477130 hasConceptScore W4313477130C2776008845 @default.
• W4313477130 hasConceptScore W4313477130C2777682441 @default.
• W4313477130 hasConceptScore W4313477130C2778557577 @default.
• W4313477130 hasConceptScore W4313477130C2778921608 @default.
• W4313477130 hasConceptScore W4313477130C2779740085 @default.
• W4313477130 hasConceptScore W4313477130C2780724011 @default.
• W4313477130 hasConceptScore W4313477130C2781301800 @default.
• W4313477130 hasConceptScore W4313477130C71924100 @default.
• W4313477130 hasLocation W43134771301 @default.
• W4313477130 hasLocation W43134771302 @default.
• W4313477130 hasLocation W43134771303 @default.
• W4313477130 hasOpenAccess W4313477130 @default.
• W4313477130 hasPrimaryLocation W43134771301 @default.
• W4313477130 hasRelatedWork W2041760800 @default.
• W4313477130 hasRelatedWork W2079603113 @default.
• W4313477130 hasRelatedWork W2469227708 @default.
• W4313477130 hasRelatedWork W2593039553 @default.
• W4313477130 hasRelatedWork W2807092282 @default.
• W4313477130 hasRelatedWork W2907896350 @default.
• W4313477130 hasRelatedWork W2923733484 @default.
• W4313477130 hasRelatedWork W3036486526 @default.
• W4313477130 hasRelatedWork W3203920577 @default.
• W4313477130 hasRelatedWork W4313477130 @default.
• W4313477130 isParatext "false" @default.
• W4313477130 isRetracted "false" @default.
• W4313477130 workType "article" @default.