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- W4313477945 abstract "We have developed a web-based tool, CoDe (Codon Deoptimization) that deoptimizes genetic sequences based on different codon usage bias, ultimately reducing expression of the corresponding protein. The tool could also deoptimize the sequence for a specific region and/or selected amino acid(s). Moreover, CoDe can highlight sites targeted by restriction enzymes in the wild-type and codon-deoptimized sequences. Importantly, our web-based tool has a user-friendly interface with flexible options to download results.The web-based tool CoDe is freely available at https://web.iitm.ac.in/bioinfo2/codeop/landing_page.html.Supplementary data are available at Bioinformatics Advances online." @default.
- W4313477945 created "2023-01-06" @default.
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- W4313477945 date "2023-01-01" @default.
- W4313477945 modified "2023-10-12" @default.
- W4313477945 title "CoDe: a web-based tool for codon deoptimization" @default.
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- W4313477945 doi "https://doi.org/10.1093/bioadv/vbac102" @default.
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