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- W4313478199 abstract "In this paper, an easy-operational, high-yielding method for the gram-scale synthesis of flavones is described by a one-pot straightforward sulfoxide-mediated Knoevenagel condensation/intermolecular oxa-Michael annulation/sulfoxide elimination process of β-(o-hydroxyaryl)-ketosulfones (dual nucleophile) and arylaldehydes (dual electrophile). The expeditious synthetic route sets up flavones, including the bond formation of one CO and one double CC bonds via a formal (5 + 1) cycloaddition. Furthermore, among them, compounds 7bn could be an excellent starting point for further development of drugs to benefit the field of anti-aging." @default.
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- W4313478199 date "2023-02-01" @default.
- W4313478199 modified "2023-10-16" @default.
- W4313478199 title "Sulfoxide-mediated approach to flavones through one-pot Knoevenagel condensation/oxa-Michael addition/sulfoxide elimination process of β-(o-hydroxyaryl)-ketosulfone with arylaldehydes" @default.
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- W4313478199 doi "https://doi.org/10.1016/j.tetlet.2022.154336" @default.
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