Matches in SemOpenAlex for { <https://semopenalex.org/work/W4313478661> ?p ?o ?g. }
- W4313478661 endingPage "642" @default.
- W4313478661 startingPage "632" @default.
- W4313478661 abstract "RNA quality control nonsense-mediated decay is involved in viral restriction in both plants and animals. However, it is not known whether two other RNA quality control pathways, nonstop decay and no-go decay, are capable of restricting viruses in plants. Here, we show that the evolutionarily conserved Pelota-Hbs1 complex negatively regulates infection of plant viruses in the family Potyviridae (termed potyvirids), the largest group of plant RNA viruses that accounts for more than half of the viral crop damage worldwide. Pelota enables the recognition of the functional G1-2A6-7 motif in the P3 cistron, which is conserved in almost all potyvirids. This allows Pelota to target the virus and act as a viral restriction factor. Furthermore, Pelota interacts with the SUMO E2-conjugating enzyme SCE1 and is SUMOylated in planta. Blocking Pelota SUMOylation disrupts the ability to recruit Hbs1 and inhibits viral RNA degradation. These findings reveal the functional importance of Pelota SUMOylation during the infection of potyvirids in plants." @default.
- W4313478661 created "2023-01-06" @default.
- W4313478661 creator A5003201408 @default.
- W4313478661 creator A5004964048 @default.
- W4313478661 creator A5013169889 @default.
- W4313478661 creator A5019560977 @default.
- W4313478661 creator A5044550018 @default.
- W4313478661 creator A5054012489 @default.
- W4313478661 creator A5058080897 @default.
- W4313478661 creator A5068553271 @default.
- W4313478661 creator A5071891458 @default.
- W4313478661 creator A5080886413 @default.
- W4313478661 creator A5081202199 @default.
- W4313478661 creator A5089986454 @default.
- W4313478661 date "2023-03-01" @default.
- W4313478661 modified "2023-10-03" @default.
- W4313478661 title "SUMOylation-modified Pelota-Hbs1 RNA surveillance complex restricts the infection of potyvirids in plants" @default.
- W4313478661 cites W1891202747 @default.
- W4313478661 cites W1926826741 @default.
- W4313478661 cites W1959908262 @default.
- W4313478661 cites W1975092906 @default.
- W4313478661 cites W1978439509 @default.
- W4313478661 cites W1981887230 @default.
- W4313478661 cites W1993987952 @default.
- W4313478661 cites W2004731223 @default.
- W4313478661 cites W2009471370 @default.
- W4313478661 cites W2013108773 @default.
- W4313478661 cites W2019696945 @default.
- W4313478661 cites W2039162233 @default.
- W4313478661 cites W2046995371 @default.
- W4313478661 cites W2055313513 @default.
- W4313478661 cites W2056372900 @default.
- W4313478661 cites W2057726003 @default.
- W4313478661 cites W2058553280 @default.
- W4313478661 cites W2080872178 @default.
- W4313478661 cites W2080929480 @default.
- W4313478661 cites W2099750055 @default.
- W4313478661 cites W2113656016 @default.
- W4313478661 cites W2115809836 @default.
- W4313478661 cites W2116122104 @default.
- W4313478661 cites W2123577912 @default.
- W4313478661 cites W2133640187 @default.
- W4313478661 cites W2133825089 @default.
- W4313478661 cites W2166964088 @default.
- W4313478661 cites W2405361759 @default.
- W4313478661 cites W2413385656 @default.
- W4313478661 cites W2590434390 @default.
- W4313478661 cites W2794765381 @default.
- W4313478661 cites W2800280129 @default.
- W4313478661 cites W2883705358 @default.
- W4313478661 cites W2887981800 @default.
- W4313478661 cites W2901325135 @default.
- W4313478661 cites W2919573452 @default.
- W4313478661 cites W2927984698 @default.
- W4313478661 cites W2952411272 @default.
- W4313478661 cites W2957622437 @default.
- W4313478661 cites W2981389845 @default.
- W4313478661 cites W3038928749 @default.
- W4313478661 cites W3118798277 @default.
- W4313478661 cites W3119567508 @default.
- W4313478661 cites W3152851559 @default.
- W4313478661 cites W3159767160 @default.
- W4313478661 cites W3184593961 @default.
- W4313478661 cites W3206358835 @default.
- W4313478661 doi "https://doi.org/10.1016/j.molp.2022.12.024" @default.
- W4313478661 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36597359" @default.
- W4313478661 hasPublicationYear "2023" @default.
- W4313478661 type Work @default.
- W4313478661 citedByCount "3" @default.
- W4313478661 countsByYear W43134786612023 @default.
- W4313478661 crossrefType "journal-article" @default.
- W4313478661 hasAuthorship W4313478661A5003201408 @default.
- W4313478661 hasAuthorship W4313478661A5004964048 @default.
- W4313478661 hasAuthorship W4313478661A5013169889 @default.
- W4313478661 hasAuthorship W4313478661A5019560977 @default.
- W4313478661 hasAuthorship W4313478661A5044550018 @default.
- W4313478661 hasAuthorship W4313478661A5054012489 @default.
- W4313478661 hasAuthorship W4313478661A5058080897 @default.
- W4313478661 hasAuthorship W4313478661A5068553271 @default.
- W4313478661 hasAuthorship W4313478661A5071891458 @default.
- W4313478661 hasAuthorship W4313478661A5080886413 @default.
- W4313478661 hasAuthorship W4313478661A5081202199 @default.
- W4313478661 hasAuthorship W4313478661A5089986454 @default.
- W4313478661 hasConcept C104317684 @default.
- W4313478661 hasConcept C159047783 @default.
- W4313478661 hasConcept C171350616 @default.
- W4313478661 hasConcept C25602115 @default.
- W4313478661 hasConcept C54355233 @default.
- W4313478661 hasConcept C67705224 @default.
- W4313478661 hasConcept C86803240 @default.
- W4313478661 hasConcept C95444343 @default.
- W4313478661 hasConceptScore W4313478661C104317684 @default.
- W4313478661 hasConceptScore W4313478661C159047783 @default.
- W4313478661 hasConceptScore W4313478661C171350616 @default.
- W4313478661 hasConceptScore W4313478661C25602115 @default.
- W4313478661 hasConceptScore W4313478661C54355233 @default.
- W4313478661 hasConceptScore W4313478661C67705224 @default.
- W4313478661 hasConceptScore W4313478661C86803240 @default.