FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4313478706> ?p ?o ?g. }

• W4313478706 endingPage "100526" @default.
• W4313478706 startingPage "100526" @default.
• W4313478706 abstract "The intertwined adoption of synthetic biology and 3D bioprinting has the potential to improve different application fields by fabricating engineered living materials (ELMs) with unnatural genetically-encoded sense & response capabilities. However, efforts are still needed to streamline the fabrication of sensing ELMs compatible with field use and improving their functional complexity. To investigate these two unmet needs, we adopted a workflow to reproducibly construct bacterial ELMs with synthetic biosensing circuits that provide red pigmentation as visible readout in response to different proof-of-concept chemical inducers. We first fabricated single-input/single-output ELMs and we demonstrated their robust performance in terms of longevity (cell viability and evolutionary stability >15 days, and long-term storage >1 month), sensing in harsh, non-sterile or nutrient-free conditions compatible with field use (soil, water, and clinical samples, including real samples from Pseudomonas aeruginosa infected patients). Then, we fabricated ELMs including multiple spatially-separated biosensor strains to engineer: level-bar materials detecting molecule concentration ranges, multi-input/multi-output devices with multiplexed sensing and information processing capabilities, and materials with cell-cell communication enabling on-demand pattern formation. Overall, we showed successful field use and multiplexed functioning of reproducibly fabricated ELMs, paving the way to a future automation of the prototyping process and boosting applications of such devices as in-situ monitoring tools or easy-to-use sensing kits." @default.
• W4313478706 created "2023-01-06" @default.
• W4313478706 creator A5006269597 @default.
• W4313478706 creator A5014372484 @default.
• W4313478706 creator A5015771184 @default.
• W4313478706 creator A5021070781 @default.
• W4313478706 creator A5057511663 @default.
• W4313478706 creator A5069653622 @default.
• W4313478706 creator A5080904375 @default.
• W4313478706 date "2023-02-01" @default.
• W4313478706 modified "2023-10-16" @default.
• W4313478706 title "Design and biofabrication of bacterial living materials with robust and multiplexed biosensing capabilities" @default.
• W4313478706 cites W1973873896 @default.
• W4313478706 cites W1975240002 @default.
• W4313478706 cites W2090609904 @default.
• W4313478706 cites W2099540110 @default.
• W4313478706 cites W2123676362 @default.
• W4313478706 cites W2164563592 @default.
• W4313478706 cites W2317153111 @default.
• W4313478706 cites W2520718776 @default.
• W4313478706 cites W2591030845 @default.
• W4313478706 cites W2760943355 @default.
• W4313478706 cites W2768425954 @default.
• W4313478706 cites W2773156981 @default.
• W4313478706 cites W2774528491 @default.
• W4313478706 cites W2794143268 @default.
• W4313478706 cites W2899288058 @default.
• W4313478706 cites W2900157726 @default.
• W4313478706 cites W2900538095 @default.
• W4313478706 cites W2903168764 @default.
• W4313478706 cites W2906406229 @default.
• W4313478706 cites W2925106348 @default.
• W4313478706 cites W2928016477 @default.
• W4313478706 cites W2954660689 @default.
• W4313478706 cites W2964863261 @default.
• W4313478706 cites W2965634581 @default.
• W4313478706 cites W2978647098 @default.
• W4313478706 cites W2982143172 @default.
• W4313478706 cites W2989837443 @default.
• W4313478706 cites W2995204009 @default.
• W4313478706 cites W3004682451 @default.
• W4313478706 cites W3036694345 @default.
• W4313478706 cites W3090459174 @default.
• W4313478706 cites W3110534520 @default.
• W4313478706 cites W3111922116 @default.
• W4313478706 cites W3117273886 @default.
• W4313478706 cites W3118207915 @default.
• W4313478706 cites W3122790033 @default.
• W4313478706 cites W3126102953 @default.
• W4313478706 cites W3127464467 @default.
• W4313478706 cites W3149090762 @default.
• W4313478706 cites W3164305030 @default.
• W4313478706 cites W3196671373 @default.
• W4313478706 cites W3205183215 @default.
• W4313478706 cites W3209204933 @default.
• W4313478706 cites W3214983972 @default.
• W4313478706 cites W4200006639 @default.
• W4313478706 cites W4290888577 @default.
• W4313478706 doi "https://doi.org/10.1016/j.mtbio.2022.100526" @default.
• W4313478706 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36632629" @default.
• W4313478706 hasPublicationYear "2023" @default.
• W4313478706 type Work @default.
• W4313478706 citedByCount "1" @default.
• W4313478706 countsByYear W43134787062023 @default.
• W4313478706 crossrefType "journal-article" @default.
• W4313478706 hasAuthorship W4313478706A5006269597 @default.
• W4313478706 hasAuthorship W4313478706A5014372484 @default.
• W4313478706 hasAuthorship W4313478706A5015771184 @default.
• W4313478706 hasAuthorship W4313478706A5021070781 @default.
• W4313478706 hasAuthorship W4313478706A5057511663 @default.
• W4313478706 hasAuthorship W4313478706A5069653622 @default.
• W4313478706 hasAuthorship W4313478706A5080904375 @default.
• W4313478706 hasBestOaLocation W43134787061 @default.
• W4313478706 hasConcept C104317684 @default.
• W4313478706 hasConcept C111919701 @default.
• W4313478706 hasConcept C124978682 @default.
• W4313478706 hasConcept C127413603 @default.
• W4313478706 hasConcept C136229726 @default.
• W4313478706 hasConcept C160756335 @default.
• W4313478706 hasConcept C171250308 @default.
• W4313478706 hasConcept C177212765 @default.
• W4313478706 hasConcept C191908910 @default.
• W4313478706 hasConcept C192562407 @default.
• W4313478706 hasConcept C19275194 @default.
• W4313478706 hasConcept C2780609957 @default.
• W4313478706 hasConcept C3019111730 @default.
• W4313478706 hasConcept C41008148 @default.
• W4313478706 hasConcept C49892992 @default.
• W4313478706 hasConcept C55493867 @default.
• W4313478706 hasConcept C60644358 @default.
• W4313478706 hasConcept C76155785 @default.
• W4313478706 hasConcept C77088390 @default.
• W4313478706 hasConcept C86803240 @default.
• W4313478706 hasConceptScore W4313478706C104317684 @default.
• W4313478706 hasConceptScore W4313478706C111919701 @default.
• W4313478706 hasConceptScore W4313478706C124978682 @default.
• W4313478706 hasConceptScore W4313478706C127413603 @default.
• W4313478706 hasConceptScore W4313478706C136229726 @default.

• next