FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4313479094> ?p ?o ?g. }

• W4313479094 endingPage "205" @default.
• W4313479094 startingPage "199" @default.
• W4313479094 abstract "It is found that there are great differences in the efficacy of quetiapine at the same dose in many patients with bipolar disorders. Therefore, therapeutic drug monitoring (TDM) is a valuable tool for guiding treatment with quetiapine. The aims of this study were to assess the relationship between serum concentration and clinical response of quetiapine in adolescents and adults with bipolar disorders in acute stage.The study design was prospective and observational. Within the naturalistic setting of a routine TDM service at the First Affiliated Hospital, Zhejiang University School of Medicine. Psychiatric symptoms were assessed using the HAMD (Hamilton Depression Scale), YRMS (Young manic rating scale) and CUDOS-M (Clinically Useful Depression Outcome Scale-Mixed Subscale). The decline of HAMD and YMRS scores was were used to assess clinical outcome of bipolar disorders respectively.169 inpatients (23.7 % male, 76.3 % female) were enrolled in the study. We found that there was a strong correlation between quetiapine serum concentrations and clinical outcomes (rs = 0.702, p < 0.001). While, quetiapine daily dose was not correlated with clinical outcome. We found that when the quetiapine serum level is >146.85 ng/ml in depression episodes patients could obtain a satisfactory treatment effect after 2 weeks of hospitalization.We found a significant positive relationship between serum concentration and clinical outcome, and also determined the serum concentration of quetiapine for the treatment of bipolar depression." @default.
• W4313479094 created "2023-01-06" @default.
• W4313479094 creator A5005657243 @default.
• W4313479094 creator A5019170759 @default.
• W4313479094 creator A5028603346 @default.
• W4313479094 creator A5037506185 @default.
• W4313479094 creator A5041088075 @default.
• W4313479094 creator A5042246049 @default.
• W4313479094 creator A5042724906 @default.
• W4313479094 creator A5043019475 @default.
• W4313479094 creator A5044383472 @default.
• W4313479094 creator A5046338175 @default.
• W4313479094 creator A5048108779 @default.
• W4313479094 creator A5048223375 @default.
• W4313479094 creator A5051841679 @default.
• W4313479094 creator A5059433125 @default.
• W4313479094 creator A5062020822 @default.
• W4313479094 creator A5070641856 @default.
• W4313479094 creator A5073753623 @default.
• W4313479094 creator A5077066454 @default.
• W4313479094 creator A5091068751 @default.
• W4313479094 date "2023-03-01" @default.
• W4313479094 modified "2023-10-18" @default.
• W4313479094 title "Relationship between serum concentration and clinical response of quetiapine in adolescents and adults with bipolar disorders in acute stage: a prospective observational study" @default.
• W4313479094 cites W1494139897 @default.
• W4313479094 cites W1530629220 @default.
• W4313479094 cites W1966127736 @default.
• W4313479094 cites W1975490782 @default.
• W4313479094 cites W1978369208 @default.
• W4313479094 cites W1983377547 @default.
• W4313479094 cites W1984759793 @default.
• W4313479094 cites W2023445503 @default.
• W4313479094 cites W2026351331 @default.
• W4313479094 cites W2033342358 @default.
• W4313479094 cites W2037091926 @default.
• W4313479094 cites W2038235070 @default.
• W4313479094 cites W2058415448 @default.
• W4313479094 cites W2080724513 @default.
• W4313479094 cites W2125138227 @default.
• W4313479094 cites W2128309600 @default.
• W4313479094 cites W2153381163 @default.
• W4313479094 cites W2167193785 @default.
• W4313479094 cites W2172850256 @default.
• W4313479094 cites W2312476090 @default.
• W4313479094 cites W2326083242 @default.
• W4313479094 cites W2341058958 @default.
• W4313479094 cites W2530783730 @default.
• W4313479094 cites W4211069648 @default.
• W4313479094 doi "https://doi.org/10.1016/j.jad.2022.12.107" @default.
• W4313479094 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36586603" @default.
• W4313479094 hasPublicationYear "2023" @default.
• W4313479094 type Work @default.
• W4313479094 citedByCount "1" @default.
• W4313479094 countsByYear W43134790942023 @default.
• W4313479094 crossrefType "journal-article" @default.
• W4313479094 hasAuthorship W4313479094A5005657243 @default.
• W4313479094 hasAuthorship W4313479094A5019170759 @default.
• W4313479094 hasAuthorship W4313479094A5028603346 @default.
• W4313479094 hasAuthorship W4313479094A5037506185 @default.
• W4313479094 hasAuthorship W4313479094A5041088075 @default.
• W4313479094 hasAuthorship W4313479094A5042246049 @default.
• W4313479094 hasAuthorship W4313479094A5042724906 @default.
• W4313479094 hasAuthorship W4313479094A5043019475 @default.
• W4313479094 hasAuthorship W4313479094A5044383472 @default.
• W4313479094 hasAuthorship W4313479094A5046338175 @default.
• W4313479094 hasAuthorship W4313479094A5048108779 @default.
• W4313479094 hasAuthorship W4313479094A5048223375 @default.
• W4313479094 hasAuthorship W4313479094A5051841679 @default.
• W4313479094 hasAuthorship W4313479094A5059433125 @default.
• W4313479094 hasAuthorship W4313479094A5062020822 @default.
• W4313479094 hasAuthorship W4313479094A5070641856 @default.
• W4313479094 hasAuthorship W4313479094A5073753623 @default.
• W4313479094 hasAuthorship W4313479094A5077066454 @default.
• W4313479094 hasAuthorship W4313479094A5091068751 @default.
• W4313479094 hasConcept C118552586 @default.
• W4313479094 hasConcept C126322002 @default.
• W4313479094 hasConcept C138496976 @default.
• W4313479094 hasConcept C139719470 @default.
• W4313479094 hasConcept C15744967 @default.
• W4313479094 hasConcept C162324750 @default.
• W4313479094 hasConcept C188816634 @default.
• W4313479094 hasConcept C23131810 @default.
• W4313479094 hasConcept C2776174506 @default.
• W4313479094 hasConcept C2776412080 @default.
• W4313479094 hasConcept C2776867660 @default.
• W4313479094 hasConcept C2776921671 @default.
• W4313479094 hasConcept C2777198177 @default.
• W4313479094 hasConcept C2778541603 @default.
• W4313479094 hasConcept C2780494398 @default.
• W4313479094 hasConcept C2780634440 @default.
• W4313479094 hasConcept C2911140283 @default.
• W4313479094 hasConcept C3018023364 @default.
• W4313479094 hasConcept C71924100 @default.
• W4313479094 hasConcept C83849319 @default.
• W4313479094 hasConceptScore W4313479094C118552586 @default.
• W4313479094 hasConceptScore W4313479094C126322002 @default.
• W4313479094 hasConceptScore W4313479094C138496976 @default.
• W4313479094 hasConceptScore W4313479094C139719470 @default.

• next