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- W4313479240 abstract ": Hemiparesis is a serious motor impairment following stroke and affecting around 65% of stroke patients. This trial attempts to study the efficacy of individualized homeopathic medicines (IHMs) in comparison with identical-looking placebos in treatment of post-stroke hemiparesis (PSH) in the mutual context of standard physiotherapy (SP).: A 3-months, open-label, randomized, placebo-controlled trial (n = 60) was conducted at the Organon of Medicine outpatient departments of National Institute of Homoeopathy, West Bengal, India. Patients were randomized to receive IHMs plus SP (n = 30) or identical-looking placebos plus SP (n = 30). Primary outcome measure was Medical Research Council (MRC) muscle strength grading scale; secondary outcomes were Stroke Impact Scale (SIS) version 2.0, Modified Ashworth Scale (MAS), and stroke recovery 0–100 visual analogue scale (VAS) scores; all measured at baseline and 3 months after intervention. Group differences and effect sizes (Cohen's d) were calculated on intention-to-treat sample.: Although overall improvements were higher in the IHMs group than placebos with small to medium effect sizes, the group differences were statistically non-significant (all P>0.05, unpaired t-tests). Improvement in SIS physical problems was significantly higher in IHMs than placebos (mean difference 2.0, 95% confidence interval 0.3 to 3.8, P = 0.025, unpaired t-test). Causticum, Lachesis mutus, and Nux vomica were the most frequently prescribed medicines. No harms, unintended effects, homeopathic aggravations or any serious adverse events were reported from either group.: There was a small, but non-significant direction of effect favoring homeopathy against placebos in treatment of post-stroke hemiparesis.: CTRI/2018/10/016196; UTN: U1111–1221–7664" @default.
- W4313479240 created "2023-01-06" @default.
- W4313479240 creator A5007121171 @default.
- W4313479240 date "2023-03-01" @default.
- W4313479240 modified "2023-10-16" @default.
- W4313479240 title "Protecting the health of future generations in the arctic through community-based participatory research and action" @default.
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- W4313479240 doi "https://doi.org/10.1016/j.explore.2022.12.008" @default.
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