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- W4313479265 endingPage "108391" @default.
- W4313479265 startingPage "108391" @default.
- W4313479265 abstract "SARS-CoV-2 infection has been a major threat to human health and a huge challenge to Medicine. In only two years, COVID-19 affected >350 million people, causing >5.6 million deaths. Chronic inflammatory states, such as diabetes or obesity, are known risk factors for COVID-19 poorest outcomes, with higher risk for disease severity and greater mortality. Metformin remains on the first line of the management of hyperglycemia in type 2 diabetes. Through its anti-inflammatory and immunomodulatory mechanisms, metformin appears as an opportunity to control the dysregulated cytokine storm secondary to SARS-CoV-2 infection. Recent studies point towards a potential protective role of metformin in the course of COVID-19, showing that current or previous treatment with metformin associates with better outcomes." @default.
- W4313479265 created "2023-01-06" @default.
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- W4313479265 date "2023-02-01" @default.
- W4313479265 modified "2023-10-17" @default.
- W4313479265 title "Metformin in SARS-CoV-2 infection: A hidden path – from altered inflammation to reduced mortality. A review from the literature" @default.
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- W4313479265 doi "https://doi.org/10.1016/j.jdiacomp.2022.108391" @default.
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