Matches in SemOpenAlex for { <https://semopenalex.org/work/W4313479562> ?p ?o ?g. }
- W4313479562 endingPage "121993" @default.
- W4313479562 startingPage "121993" @default.
- W4313479562 abstract "Integrating the imaging techniques of near-infrared fluorescence (NIRF) and photoacoustic (PA) can make up for each other and provide more useful medical information. Ratiometric imaging activated by disease-associated biomarkers can further augment imaging specificity. However, very few studies have employed the NIRF/PA dual-modal ratiometric imaging to improve the accuracy and specificity of disease diagnosis to date. In this paper, we present the synthesis of a nitric oxide (NO)-activated ratiometric NIRF/PA dual-modal nanoprobe RAPNP for in vivo NO imaging. The ratiometric imaging function was achieved jointly by a NO/acidity-responsive molecule DTP-BTDA and a nonresponsive fluorophore DTP-BBTD. In these fluorophores, the dithienopyrrole (DTP) moiety had strong electron-donating ability and imparted strong intramolecular charge transfer and relatively long emission wavelengths. The BTDA moiety in DTP-BTDA could be rapidly oxidized by NO under weak acidic environments, achieving the NIRF and PA signal activation. By using RAPNP as a contrast agent, we achieved the ratiometric detection of the endogenous NO in inflammatory bowel disease by NIRF/PA dual-modal imaging. This work provides the first case of the NIRF/PA dual-signal ratiometric probe for the real-time detection of NO in vivo." @default.
- W4313479562 created "2023-01-06" @default.
- W4313479562 creator A5020759595 @default.
- W4313479562 creator A5023307885 @default.
- W4313479562 creator A5023984040 @default.
- W4313479562 creator A5025288002 @default.
- W4313479562 creator A5053985564 @default.
- W4313479562 creator A5055115466 @default.
- W4313479562 creator A5056776307 @default.
- W4313479562 creator A5057000014 @default.
- W4313479562 creator A5070350314 @default.
- W4313479562 creator A5071573941 @default.
- W4313479562 date "2023-03-01" @default.
- W4313479562 modified "2023-10-18" @default.
- W4313479562 title "A ratiometric near-infrared fluorescence/photoacoustic dual-modal probe with strong donor dithienopyrrole for in vivo nitric oxide detection" @default.
- W4313479562 cites W1973412085 @default.
- W4313479562 cites W1977871291 @default.
- W4313479562 cites W1981147276 @default.
- W4313479562 cites W1982388837 @default.
- W4313479562 cites W2036642277 @default.
- W4313479562 cites W2050023299 @default.
- W4313479562 cites W2052475141 @default.
- W4313479562 cites W2067590620 @default.
- W4313479562 cites W2124271278 @default.
- W4313479562 cites W2197175751 @default.
- W4313479562 cites W2315800446 @default.
- W4313479562 cites W2326737729 @default.
- W4313479562 cites W2332524669 @default.
- W4313479562 cites W2338274451 @default.
- W4313479562 cites W2569658671 @default.
- W4313479562 cites W2573995939 @default.
- W4313479562 cites W2591288833 @default.
- W4313479562 cites W2614165899 @default.
- W4313479562 cites W2749694032 @default.
- W4313479562 cites W2763535727 @default.
- W4313479562 cites W2765750234 @default.
- W4313479562 cites W2784082116 @default.
- W4313479562 cites W2793078295 @default.
- W4313479562 cites W2890611249 @default.
- W4313479562 cites W2900755780 @default.
- W4313479562 cites W2901287979 @default.
- W4313479562 cites W2908547111 @default.
- W4313479562 cites W2965605561 @default.
- W4313479562 cites W2968521490 @default.
- W4313479562 cites W2987177326 @default.
- W4313479562 cites W2995891414 @default.
- W4313479562 cites W2999682224 @default.
- W4313479562 cites W3010187002 @default.
- W4313479562 cites W3012484408 @default.
- W4313479562 cites W3027285375 @default.
- W4313479562 cites W3038021880 @default.
- W4313479562 cites W3048725315 @default.
- W4313479562 cites W3123497355 @default.
- W4313479562 cites W3127018001 @default.
- W4313479562 cites W3133981896 @default.
- W4313479562 cites W3159293225 @default.
- W4313479562 cites W3174697364 @default.
- W4313479562 cites W344611212 @default.
- W4313479562 cites W4200146459 @default.
- W4313479562 doi "https://doi.org/10.1016/j.biomaterials.2023.121993" @default.
- W4313479562 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36628889" @default.
- W4313479562 hasPublicationYear "2023" @default.
- W4313479562 type Work @default.
- W4313479562 citedByCount "2" @default.
- W4313479562 countsByYear W43134795622023 @default.
- W4313479562 crossrefType "journal-article" @default.
- W4313479562 hasAuthorship W4313479562A5020759595 @default.
- W4313479562 hasAuthorship W4313479562A5023307885 @default.
- W4313479562 hasAuthorship W4313479562A5023984040 @default.
- W4313479562 hasAuthorship W4313479562A5025288002 @default.
- W4313479562 hasAuthorship W4313479562A5053985564 @default.
- W4313479562 hasAuthorship W4313479562A5055115466 @default.
- W4313479562 hasAuthorship W4313479562A5056776307 @default.
- W4313479562 hasAuthorship W4313479562A5057000014 @default.
- W4313479562 hasAuthorship W4313479562A5070350314 @default.
- W4313479562 hasAuthorship W4313479562A5071573941 @default.
- W4313479562 hasConcept C120665830 @default.
- W4313479562 hasConcept C121332964 @default.
- W4313479562 hasConcept C136339569 @default.
- W4313479562 hasConcept C150903083 @default.
- W4313479562 hasConcept C155672457 @default.
- W4313479562 hasConcept C16387964 @default.
- W4313479562 hasConcept C171250308 @default.
- W4313479562 hasConcept C178790620 @default.
- W4313479562 hasConcept C185592680 @default.
- W4313479562 hasConcept C192562407 @default.
- W4313479562 hasConcept C207001950 @default.
- W4313479562 hasConcept C2776568683 @default.
- W4313479562 hasConcept C2778617687 @default.
- W4313479562 hasConcept C2781188995 @default.
- W4313479562 hasConcept C46141821 @default.
- W4313479562 hasConcept C519581460 @default.
- W4313479562 hasConcept C54932901 @default.
- W4313479562 hasConcept C57477423 @default.
- W4313479562 hasConcept C60644358 @default.
- W4313479562 hasConcept C86803240 @default.
- W4313479562 hasConcept C91881484 @default.
- W4313479562 hasConceptScore W4313479562C120665830 @default.