FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4313480031> ?p ?o ?g. }

• W4313480031 endingPage "112646" @default.
• W4313480031 startingPage "112646" @default.
• W4313480031 abstract "Hydrogen sulfide (H2S) as a key fundamental gasotransmitter regulates various biological processes, and the incontrollable H2S is essentially associated with the occurrence and development of multiple diseases, including cancers. Photodynamic therapy (PDT), as an invasive tumor treatment technology, has also attracted great attentions. Due to the key role of elevated H2S in cancers, integrating H2S depletion/recognition and PDT should be an effective strategy to enhance anticancer performance. In this work, we report a H2S depletion aided PDT platform (3RAX-NBD) by the chemical ligation of 3RAX and NBD. 3RAX-NBD can react rapidly with H2S and generate a novel 3RAX derivative compound 3 with increased fluorescence in vitro and in vivo. More notably, 3RAX-NBD can effectively kill multiple cancer cells through in situ irradiation, and 3RAX-NBD also has prominent anticancer effects on 4 T1 tumor-bearing BALB/c female mice with no notably toxic side effects. We believe that our H2S depletion aided PDT platform may provide a powerful tool for studying the key roles of H2S in diseases, and also give another promising candidate for cancer treatment." @default.
• W4313480031 created "2023-01-06" @default.
• W4313480031 creator A5009232538 @default.
• W4313480031 creator A5015657009 @default.
• W4313480031 creator A5021418808 @default.
• W4313480031 creator A5045067652 @default.
• W4313480031 creator A5053956165 @default.
• W4313480031 creator A5060859362 @default.
• W4313480031 creator A5073531557 @default.
• W4313480031 creator A5084462717 @default.
• W4313480031 date "2023-02-01" @default.
• W4313480031 modified "2023-10-14" @default.
• W4313480031 title "Development of novel hydrogen sulfide depletion aided platform for photodynamic therapy with enhanced anticancer performance" @default.
• W4313480031 cites W1596848781 @default.
• W4313480031 cites W1655368476 @default.
• W4313480031 cites W1971154550 @default.
• W4313480031 cites W1981512919 @default.
• W4313480031 cites W1982895791 @default.
• W4313480031 cites W1983513124 @default.
• W4313480031 cites W2021215174 @default.
• W4313480031 cites W2028606217 @default.
• W4313480031 cites W2040934284 @default.
• W4313480031 cites W2048678284 @default.
• W4313480031 cites W2143912446 @default.
• W4313480031 cites W2160525912 @default.
• W4313480031 cites W2320589001 @default.
• W4313480031 cites W2321902475 @default.
• W4313480031 cites W2342244420 @default.
• W4313480031 cites W2572445669 @default.
• W4313480031 cites W2589357466 @default.
• W4313480031 cites W2598437826 @default.
• W4313480031 cites W2784707844 @default.
• W4313480031 cites W2803997671 @default.
• W4313480031 cites W2885010761 @default.
• W4313480031 cites W3021720022 @default.
• W4313480031 cites W3023609649 @default.
• W4313480031 cites W3081751221 @default.
• W4313480031 cites W3159080729 @default.
• W4313480031 cites W3165174273 @default.
• W4313480031 cites W3195977088 @default.
• W4313480031 cites W4205515654 @default.
• W4313480031 cites W4236311752 @default.
• W4313480031 cites W4237417817 @default.
• W4313480031 cites W4283708934 @default.
• W4313480031 doi "https://doi.org/10.1016/j.jphotobiol.2022.112646" @default.
• W4313480031 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36638557" @default.
• W4313480031 hasPublicationYear "2023" @default.
• W4313480031 type Work @default.
• W4313480031 citedByCount "1" @default.
• W4313480031 countsByYear W43134800312023 @default.
• W4313480031 crossrefType "journal-article" @default.
• W4313480031 hasAuthorship W4313480031A5009232538 @default.
• W4313480031 hasAuthorship W4313480031A5015657009 @default.
• W4313480031 hasAuthorship W4313480031A5021418808 @default.
• W4313480031 hasAuthorship W4313480031A5045067652 @default.
• W4313480031 hasAuthorship W4313480031A5053956165 @default.
• W4313480031 hasAuthorship W4313480031A5060859362 @default.
• W4313480031 hasAuthorship W4313480031A5073531557 @default.
• W4313480031 hasAuthorship W4313480031A5084462717 @default.
• W4313480031 hasConcept C121608353 @default.
• W4313480031 hasConcept C126322002 @default.
• W4313480031 hasConcept C150903083 @default.
• W4313480031 hasConcept C178790620 @default.
• W4313480031 hasConcept C185592680 @default.
• W4313480031 hasConcept C202751555 @default.
• W4313480031 hasConcept C207001950 @default.
• W4313480031 hasConcept C2780564542 @default.
• W4313480031 hasConcept C2781323092 @default.
• W4313480031 hasConcept C502942594 @default.
• W4313480031 hasConcept C518881349 @default.
• W4313480031 hasConcept C55493867 @default.
• W4313480031 hasConcept C71924100 @default.
• W4313480031 hasConcept C86803240 @default.
• W4313480031 hasConceptScore W4313480031C121608353 @default.
• W4313480031 hasConceptScore W4313480031C126322002 @default.
• W4313480031 hasConceptScore W4313480031C150903083 @default.
• W4313480031 hasConceptScore W4313480031C178790620 @default.
• W4313480031 hasConceptScore W4313480031C185592680 @default.
• W4313480031 hasConceptScore W4313480031C202751555 @default.
• W4313480031 hasConceptScore W4313480031C207001950 @default.
• W4313480031 hasConceptScore W4313480031C2780564542 @default.
• W4313480031 hasConceptScore W4313480031C2781323092 @default.
• W4313480031 hasConceptScore W4313480031C502942594 @default.
• W4313480031 hasConceptScore W4313480031C518881349 @default.
• W4313480031 hasConceptScore W4313480031C55493867 @default.
• W4313480031 hasConceptScore W4313480031C71924100 @default.
• W4313480031 hasConceptScore W4313480031C86803240 @default.
• W4313480031 hasFunder F4320322186 @default.
• W4313480031 hasLocation W43134800311 @default.
• W4313480031 hasLocation W43134800312 @default.
• W4313480031 hasOpenAccess W4313480031 @default.
• W4313480031 hasPrimaryLocation W43134800311 @default.
• W4313480031 hasRelatedWork W121222705 @default.
• W4313480031 hasRelatedWork W1987055491 @default.
• W4313480031 hasRelatedWork W1999394278 @default.
• W4313480031 hasRelatedWork W2050852318 @default.
• W4313480031 hasRelatedWork W2061776930 @default.
• W4313480031 hasRelatedWork W2089511639 @default.

• next