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- W4313480198 abstract "This study examined the role of Tfh and Treg associated molecules also known as checkpoint molecules, their ligands, and IL-21 in myasthenia gravis (MG) pathogenesis. Serum levels of sPD-1, sPD-L1, sICOS, sICOSLG, sCTLA4, and IL-21 were measured in 39 patients with acetylcholine receptor (AChR) antibody-positive generalized MG and 27 controls. sPD-1 and IL-21 levels were higher in MG patients than in controls. Additionally, sPD-1 levels correlated positively with the levels of IL-21, sICOSLG, sCTLA4, and AChR antibody titers. sICOS are correlated with MGADL and AChR antibody titers. These Tfh associated molecules could be used as biomarkers of MG disease activity." @default.
- W4313480198 created "2023-01-06" @default.
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- W4313480198 date "2023-02-01" @default.
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- W4313480198 title "Role of soluble forms of follicular helper T-cell membrane molecules in the pathogenesis of myasthenia gravis" @default.
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- W4313480198 doi "https://doi.org/10.1016/j.jneuroim.2022.578014" @default.
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