Matches in SemOpenAlex for { <https://semopenalex.org/work/W4313481987> ?p ?o ?g. }
- W4313481987 abstract "Abstract A facile, catalyst‐ and solvent‐ free, three‐component reaction was developed for the synthesis of tetrasubstituted pyrroles at room temperature and under white light. The reaction proceeds via enamine formation between primary amines with 1,3‐dicarbonyl compounds followed by Michael addition with β‐nitro styrene and subsequent intramolecular cyclization and aromatization to yield 1,2,3,4‐tetrasubstituted pyrroles in good to excellent yields. Further, the present strategy is highly atom‐economical and environmentally benign. The preliminary in vitro cytotoxic studies on a set of compounds were performed against Hepatocellular carcinoma cells (HepG2) and one of the compounds 4 ac showed significant activity with an IC 50 value of 17.82 μM." @default.
- W4313481987 created "2023-01-06" @default.
- W4313481987 creator A5002771501 @default.
- W4313481987 creator A5014314813 @default.
- W4313481987 creator A5067675055 @default.
- W4313481987 creator A5078717581 @default.
- W4313481987 creator A5082422953 @default.
- W4313481987 creator A5086836828 @default.
- W4313481987 date "2023-01-02" @default.
- W4313481987 modified "2023-10-12" @default.
- W4313481987 title "A Catalyst‐ and Solvent‐ Free Synthesis of Tetra‐Substituted Pyrroles by Multicomponent Reaction" @default.
- W4313481987 cites W1928717079 @default.
- W4313481987 cites W1929569495 @default.
- W4313481987 cites W194034590 @default.
- W4313481987 cites W1963712369 @default.
- W4313481987 cites W1965901337 @default.
- W4313481987 cites W1968033597 @default.
- W4313481987 cites W1970705590 @default.
- W4313481987 cites W1970886364 @default.
- W4313481987 cites W1983116130 @default.
- W4313481987 cites W1984506844 @default.
- W4313481987 cites W1984728366 @default.
- W4313481987 cites W1985000437 @default.
- W4313481987 cites W1985017998 @default.
- W4313481987 cites W1985773586 @default.
- W4313481987 cites W1991658992 @default.
- W4313481987 cites W1993648193 @default.
- W4313481987 cites W1994708868 @default.
- W4313481987 cites W1997129733 @default.
- W4313481987 cites W2001136400 @default.
- W4313481987 cites W2002968096 @default.
- W4313481987 cites W2005775306 @default.
- W4313481987 cites W2006784816 @default.
- W4313481987 cites W2006986161 @default.
- W4313481987 cites W2010814335 @default.
- W4313481987 cites W2012262356 @default.
- W4313481987 cites W2022323077 @default.
- W4313481987 cites W2023325881 @default.
- W4313481987 cites W2030237878 @default.
- W4313481987 cites W2030793291 @default.
- W4313481987 cites W2031382760 @default.
- W4313481987 cites W2035438994 @default.
- W4313481987 cites W2046019867 @default.
- W4313481987 cites W2047255477 @default.
- W4313481987 cites W2050634511 @default.
- W4313481987 cites W2055025998 @default.
- W4313481987 cites W2055973128 @default.
- W4313481987 cites W2056589418 @default.
- W4313481987 cites W2057351000 @default.
- W4313481987 cites W2061767371 @default.
- W4313481987 cites W2064645122 @default.
- W4313481987 cites W2071851966 @default.
- W4313481987 cites W2072106384 @default.
- W4313481987 cites W2078634145 @default.
- W4313481987 cites W2079152086 @default.
- W4313481987 cites W2082464315 @default.
- W4313481987 cites W2082584391 @default.
- W4313481987 cites W2084316929 @default.
- W4313481987 cites W2089387138 @default.
- W4313481987 cites W2089956435 @default.
- W4313481987 cites W2095175812 @default.
- W4313481987 cites W2096060622 @default.
- W4313481987 cites W2101523078 @default.
- W4313481987 cites W2114809965 @default.
- W4313481987 cites W2121577438 @default.
- W4313481987 cites W2124660242 @default.
- W4313481987 cites W2125437828 @default.
- W4313481987 cites W2130449674 @default.
- W4313481987 cites W2139583920 @default.
- W4313481987 cites W2139906512 @default.
- W4313481987 cites W2143556825 @default.
- W4313481987 cites W2149669555 @default.
- W4313481987 cites W2153593769 @default.
- W4313481987 cites W2155465734 @default.
- W4313481987 cites W2155508038 @default.
- W4313481987 cites W2157940531 @default.
- W4313481987 cites W2158265387 @default.
- W4313481987 cites W2167940839 @default.
- W4313481987 cites W2269962988 @default.
- W4313481987 cites W2279540218 @default.
- W4313481987 cites W2303200439 @default.
- W4313481987 cites W2313064857 @default.
- W4313481987 cites W2322904520 @default.
- W4313481987 cites W2325387371 @default.
- W4313481987 cites W2326595818 @default.
- W4313481987 cites W2416554105 @default.
- W4313481987 cites W2510712630 @default.
- W4313481987 cites W2511409636 @default.
- W4313481987 cites W2531784091 @default.
- W4313481987 cites W2588037556 @default.
- W4313481987 cites W2601724453 @default.
- W4313481987 cites W2603953108 @default.
- W4313481987 cites W2609787716 @default.
- W4313481987 cites W2614347335 @default.
- W4313481987 cites W2765329874 @default.
- W4313481987 cites W2769992005 @default.
- W4313481987 cites W2806879828 @default.
- W4313481987 cites W2890102659 @default.
- W4313481987 cites W2911237047 @default.
- W4313481987 cites W2911262147 @default.