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- W4313483922 abstract "Dr. Starzl the father of Liver Transplantation had written that ‘what was inconceivable yesterday, and barely achievable today, often becomes routine tomorrow’. Organ transplantation is the only option to improve the quality of life and improve the life expectancy in patients with end-stage organ failure. Organ donation can be done after death either after death by the neurological criteria (Donation after Brain Death [DBD]) or death by the cardiorespiratory criteria [Donation after Cardiac Death (DCD)] or Living Donor Donation. Living donor programs can be harbingers of illegal organ trade. Consideration for organ and tissue donation should be routine part of care in any ICU or ED. Emphasis should be placed on presumptive consent rather than opt in registration. The increasing need for DCD necessitates the development of appropriate guidelines and protocols and establishing professional training and education programmes. These guidelines and protocols should holistically encompass the principles of ‘end of life care’, the ‘dead donor rule’, the legal, ethical, moral and professional aspects of DCD and should be universally acceptable. Organs retrieved from DCD donors are exposed to greater ischaemia as compared to DBD. Standard static cold storage (SCS) remains the gold standard in graft preservation for all organs but is found to be inefficient and can lead to wastage of available organs. Machine Perfusion has shown the greatest potential in this aspect of organ preservation and various modifications of the same are currently being evaluated and applied in regular clinical practice. MP is expected to provide a physiological environment by circulation of an oxygen rich perfusate through the organ either through normothermia or hypothermia" @default.
- W4313483922 created "2023-01-06" @default.
- W4313483922 creator A5029178369 @default.
- W4313483922 date "2023-01-01" @default.
- W4313483922 modified "2023-09-27" @default.
- W4313483922 title "Donation After Circulatory Death" @default.
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- W4313483922 doi "https://doi.org/10.1007/978-981-19-6045-1_26" @default.
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