FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4313484879> ?p ?o ?g. }

• W4313484879 abstract "Abstract Background Fibroblast growth factor receptor 1(FGFR1) plays a indispensable role in the tumorigenesis and therapy. However, the relationship of FGFR1 in the prognosis and immune infiltration remains to be elucidated. Methods FGFR1 expression was analyzed in different databases, respectively. Clinicopathological parameters and survival datas were analyzed by Kaplan-Meier plotter. The correlations between FGFR1 and immune infiltrates were conducted by Tumor Immune Estimation Resource (TIMER). Genetic alterations of FGFR1 and DNA methylation were assessed by cBioPortal and MethSuev. FGFR1 co-expressed and functional networks were analyzed by LinkedOmics in nonsmall cell lung cancer (NSCLC). Results FGFR1 expression was significantly lower in NSCLC than normal tissues, and high FGFR1 significantly correlated with favorable overall survival (OS) in lung squamous cell carcinomas (LUSC). FGFR1 can predict tumor prognosis independently of other factors in OS by Cox analyses. Moreover, FGFR1 expression was significantly correlated with the infiltrating multiple tumor immune cell markers both in NSCLC. Additonaly, the gene alteration and prognostic value of the DNA methylation patterns of FGFR1 in NSCLC were carried out. Furthermore, a functional network analysis confirmed the function of FGFR1 in regulating tumorigenesis and vasculogenesis. Conclusions FGFR1 may be used as a biomarker for prognosis and evaluating immune infiltration in NSCLC." @default.
• W4313484879 created "2023-01-06" @default.
• W4313484879 creator A5001165522 @default.
• W4313484879 creator A5006349365 @default.
• W4313484879 creator A5051663301 @default.
• W4313484879 creator A5055249391 @default.
• W4313484879 date "2023-01-04" @default.
• W4313484879 modified "2023-10-17" @default.
• W4313484879 title "Correlation between prognostic indicator FGFR1 and immune infiltrates in non‑small cell lung cancer" @default.
• W4313484879 cites W1525117983 @default.
• W4313484879 cites W1894751757 @default.
• W4313484879 cites W1971620413 @default.
• W4313484879 cites W1974771466 @default.
• W4313484879 cites W1977918192 @default.
• W4313484879 cites W1988476050 @default.
• W4313484879 cites W1993142403 @default.
• W4313484879 cites W2027239974 @default.
• W4313484879 cites W2046692530 @default.
• W4313484879 cites W2046786765 @default.
• W4313484879 cites W2054195724 @default.
• W4313484879 cites W2056983875 @default.
• W4313484879 cites W2081855695 @default.
• W4313484879 cites W2082484803 @default.
• W4313484879 cites W2082668371 @default.
• W4313484879 cites W2093235552 @default.
• W4313484879 cites W2096019143 @default.
• W4313484879 cites W2098546316 @default.
• W4313484879 cites W2102007289 @default.
• W4313484879 cites W2126496132 @default.
• W4313484879 cites W2132237962 @default.
• W4313484879 cites W2149441684 @default.
• W4313484879 cites W2150770343 @default.
• W4313484879 cites W2154758108 @default.
• W4313484879 cites W2159060826 @default.
• W4313484879 cites W2180089959 @default.
• W4313484879 cites W2272984102 @default.
• W4313484879 cites W2312662599 @default.
• W4313484879 cites W2395507246 @default.
• W4313484879 cites W2399999257 @default.
• W4313484879 cites W2504606663 @default.
• W4313484879 cites W2507880739 @default.
• W4313484879 cites W2508069933 @default.
• W4313484879 cites W2531294657 @default.
• W4313484879 cites W2533941196 @default.
• W4313484879 cites W2537892258 @default.
• W4313484879 cites W2546654144 @default.
• W4313484879 cites W2550856922 @default.
• W4313484879 cites W2587048937 @default.
• W4313484879 cites W2600903921 @default.
• W4313484879 cites W2607129810 @default.
• W4313484879 cites W2609512644 @default.
• W4313484879 cites W2610643018 @default.
• W4313484879 cites W2618618401 @default.
• W4313484879 cites W2626344037 @default.
• W4313484879 cites W2739714794 @default.
• W4313484879 cites W2765224588 @default.
• W4313484879 cites W2779695949 @default.
• W4313484879 cites W2897182820 @default.
• W4313484879 cites W2898174432 @default.
• W4313484879 cites W2900048176 @default.
• W4313484879 cites W2963572064 @default.
• W4313484879 cites W2979035301 @default.
• W4313484879 cites W3038129235 @default.
• W4313484879 cites W3089009365 @default.
• W4313484879 cites W3115349904 @default.
• W4313484879 cites W3119970173 @default.
• W4313484879 cites W3131416308 @default.
• W4313484879 cites W3159658288 @default.
• W4313484879 cites W3160599800 @default.
• W4313484879 doi "https://doi.org/10.21203/rs.3.rs-2421144/v1" @default.
• W4313484879 hasPublicationYear "2023" @default.
• W4313484879 type Work @default.
• W4313484879 citedByCount "0" @default.
• W4313484879 crossrefType "posted-content" @default.
• W4313484879 hasAuthorship W4313484879A5001165522 @default.
• W4313484879 hasAuthorship W4313484879A5006349365 @default.
• W4313484879 hasAuthorship W4313484879A5051663301 @default.
• W4313484879 hasAuthorship W4313484879A5055249391 @default.
• W4313484879 hasBestOaLocation W43134848791 @default.
• W4313484879 hasConcept C121608353 @default.
• W4313484879 hasConcept C126322002 @default.
• W4313484879 hasConcept C143998085 @default.
• W4313484879 hasConcept C170493617 @default.
• W4313484879 hasConcept C203014093 @default.
• W4313484879 hasConcept C2776256026 @default.
• W4313484879 hasConcept C49418065 @default.
• W4313484879 hasConcept C502942594 @default.
• W4313484879 hasConcept C555283112 @default.
• W4313484879 hasConcept C71924100 @default.
• W4313484879 hasConcept C74373430 @default.
• W4313484879 hasConcept C86803240 @default.
• W4313484879 hasConcept C8891405 @default.
• W4313484879 hasConceptScore W4313484879C121608353 @default.
• W4313484879 hasConceptScore W4313484879C126322002 @default.
• W4313484879 hasConceptScore W4313484879C143998085 @default.
• W4313484879 hasConceptScore W4313484879C170493617 @default.
• W4313484879 hasConceptScore W4313484879C203014093 @default.
• W4313484879 hasConceptScore W4313484879C2776256026 @default.
• W4313484879 hasConceptScore W4313484879C49418065 @default.
• W4313484879 hasConceptScore W4313484879C502942594 @default.

• next