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- W4313485855 abstract "In the present study, phycoerythrin pigment protein was extracted and purified from Gracilaria corticata (marine macroalga). The concentration of phycoerythrin (PE) obtained from G. corticata was 0.15 mg/ml (fresh weight). In this study, phycoerythrin expressed less antimicrobial activity against pathogens but found effective in total antioxidant activity (264.90 ± 10.20 μg/ml), DPPH scavenging effect (22.91 ± 1.90%) and ferrous ion chelating ability (26.06 ± 1.60%). Further, the cytotoxicity assay of PE using colon cancer cells such as SW620 and HCT-116 was tested. Different concentrations (2, 4, 8, 16, 32 μl) of phycoerythrin was tested in MTT assay after 24 h and 48 h incubation. The MTT assay concludes that increasing concentration of phycoerythrin (4.8 μg) decreases the cell viability to 42% after 48 h in SW 620 cell line. Whereas in the HCT 116 cell line the increasing concentration of phycoerythrin induces the cell growth on 24 h but later drastically reduced growth of cell line (39%) was observed after 48 h time in 4.8 μg of PE. From this preliminary study, the phycoerythrin pigment extracted from Gracilaria corticata proved to be a potential molecule of interest for cancer studies and diagnosis." @default.
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- W4313485855 date "2023-01-01" @default.
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- W4313485855 title "Evaluation of antimicrobial, antioxidant and cytotoxicity potential of R-phycoerythrin extracted from Gracilaria corticata seaweed" @default.
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- W4313485855 doi "https://doi.org/10.1016/j.crgsc.2022.100352" @default.
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