FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4313487239> ?p ?o ?g. }

• W4313487239 abstract "Abstract Background: Cangrelor, the first intravenous P2Y 12 inhibitor (P2Y 12 -I), has been approved on the basis of three large RCTs from the CHAMPION program which nevertheless have been criticized for the low bleeding risk of the enrolled patients, the large quote of chronic coronary syndromes (CCS), and the use of Clopidogrel as control arm even in the setting of acute coronary syndromes (ACS). We sought to investigate, in the setting of ACS, the comparative performance of Cangrelor in terms of in-hospital ischemic and haemorrhagic outcomes compared with the current gold-standard of oral P2Y 12 -I. Methods: The study retrospectively enrolled 686 consecutive patients admitted to the Divisions of Cardiology of Policlinico of Bari and L. Bonomo Hospital of Andria for ACS and treated with percutaneous coronary intervention (PCI). The study population was divided according to the P2Y 12 -I treatment strategy in two groups: patients given an oral P2Y 12 -I and patients receiving Cangrelor in the CathLab followed by an oral P2Y 12 -I. Clinical endpoints included death, ischemic and bleeding events occurring during hospital stay. Results: Cangrelor treated patients presented higher clinical risk profile at presentation and faced higher death rate. However, after PS matching, in-hospital mortality resulted comparable between the groups and Cangrelor use was associated with reduced in-hospital definite stent thrombosis (p=0.03). Conclusions: Data from our real-world registry highlight that, in the setting of ACS, Cangrelor is prevalently used in patients with very challenging clinical presentations. The adjusted analysis provides for the first time promising data on stent thrombosis reduction associated with Cangrelor use." @default.
• W4313487239 created "2023-01-06" @default.
• W4313487239 creator A5004101295 @default.
• W4313487239 creator A5007494874 @default.
• W4313487239 creator A5024791802 @default.
• W4313487239 creator A5027483298 @default.
• W4313487239 creator A5034876062 @default.
• W4313487239 creator A5037881065 @default.
• W4313487239 creator A5038265132 @default.
• W4313487239 creator A5048514801 @default.
• W4313487239 creator A5052617126 @default.
• W4313487239 creator A5063125115 @default.
• W4313487239 creator A5063939893 @default.
• W4313487239 creator A5068374739 @default.
• W4313487239 creator A5082404230 @default.
• W4313487239 date "2023-01-04" @default.
• W4313487239 modified "2023-09-26" @default.
• W4313487239 title "Comparative effectiveness of Cangrelor in patients with acute coronary syndrome undergoing percutaneous coronary intervention: Insights from the multicenter M.O.Ca. registry" @default.
• W4313487239 cites W1596397105 @default.
• W4313487239 cites W2049120615 @default.
• W4313487239 cites W2050027713 @default.
• W4313487239 cites W2071686230 @default.
• W4313487239 cites W2122779695 @default.
• W4313487239 cites W2123112974 @default.
• W4313487239 cites W2127090290 @default.
• W4313487239 cites W2150655309 @default.
• W4313487239 cites W2166950143 @default.
• W4313487239 cites W2515533568 @default.
• W4313487239 cites W2532584865 @default.
• W4313487239 cites W2593571361 @default.
• W4313487239 cites W2626530860 @default.
• W4313487239 cites W2752033985 @default.
• W4313487239 cites W2754054868 @default.
• W4313487239 cites W2804073465 @default.
• W4313487239 cites W2893091384 @default.
• W4313487239 cites W2913302460 @default.
• W4313487239 cites W2941206839 @default.
• W4313487239 cites W2946796958 @default.
• W4313487239 cites W2969470858 @default.
• W4313487239 cites W2989714602 @default.
• W4313487239 cites W3162195278 @default.
• W4313487239 cites W4225991527 @default.
• W4313487239 cites W4238277289 @default.
• W4313487239 cites W4283314382 @default.
• W4313487239 doi "https://doi.org/10.21203/rs.3.rs-2393589/v1" @default.
• W4313487239 hasPublicationYear "2023" @default.
• W4313487239 type Work @default.
• W4313487239 citedByCount "0" @default.
• W4313487239 crossrefType "posted-content" @default.
• W4313487239 hasAuthorship W4313487239A5004101295 @default.
• W4313487239 hasAuthorship W4313487239A5007494874 @default.
• W4313487239 hasAuthorship W4313487239A5024791802 @default.
• W4313487239 hasAuthorship W4313487239A5027483298 @default.
• W4313487239 hasAuthorship W4313487239A5034876062 @default.
• W4313487239 hasAuthorship W4313487239A5037881065 @default.
• W4313487239 hasAuthorship W4313487239A5038265132 @default.
• W4313487239 hasAuthorship W4313487239A5048514801 @default.
• W4313487239 hasAuthorship W4313487239A5052617126 @default.
• W4313487239 hasAuthorship W4313487239A5063125115 @default.
• W4313487239 hasAuthorship W4313487239A5063939893 @default.
• W4313487239 hasAuthorship W4313487239A5068374739 @default.
• W4313487239 hasAuthorship W4313487239A5082404230 @default.
• W4313487239 hasBestOaLocation W43134872391 @default.
• W4313487239 hasConcept C126322002 @default.
• W4313487239 hasConcept C164705383 @default.
• W4313487239 hasConcept C2776708134 @default.
• W4313487239 hasConcept C2777628954 @default.
• W4313487239 hasConcept C2777698277 @default.
• W4313487239 hasConcept C2777849778 @default.
• W4313487239 hasConcept C2780400711 @default.
• W4313487239 hasConcept C45393284 @default.
• W4313487239 hasConcept C49059817 @default.
• W4313487239 hasConcept C500558357 @default.
• W4313487239 hasConcept C535046627 @default.
• W4313487239 hasConcept C71924100 @default.
• W4313487239 hasConceptScore W4313487239C126322002 @default.
• W4313487239 hasConceptScore W4313487239C164705383 @default.
• W4313487239 hasConceptScore W4313487239C2776708134 @default.
• W4313487239 hasConceptScore W4313487239C2777628954 @default.
• W4313487239 hasConceptScore W4313487239C2777698277 @default.
• W4313487239 hasConceptScore W4313487239C2777849778 @default.
• W4313487239 hasConceptScore W4313487239C2780400711 @default.
• W4313487239 hasConceptScore W4313487239C45393284 @default.
• W4313487239 hasConceptScore W4313487239C49059817 @default.
• W4313487239 hasConceptScore W4313487239C500558357 @default.
• W4313487239 hasConceptScore W4313487239C535046627 @default.
• W4313487239 hasConceptScore W4313487239C71924100 @default.
• W4313487239 hasLocation W43134872391 @default.
• W4313487239 hasOpenAccess W4313487239 @default.
• W4313487239 hasPrimaryLocation W43134872391 @default.
• W4313487239 hasRelatedWork W1534422272 @default.
• W4313487239 hasRelatedWork W2001468576 @default.
• W4313487239 hasRelatedWork W2081030005 @default.
• W4313487239 hasRelatedWork W2313052852 @default.
• W4313487239 hasRelatedWork W2367046339 @default.
• W4313487239 hasRelatedWork W2386452320 @default.
• W4313487239 hasRelatedWork W2388626260 @default.
• W4313487239 hasRelatedWork W2389313759 @default.
• W4313487239 hasRelatedWork W4287010319 @default.
• W4313487239 hasRelatedWork W4311497569 @default.

• next