Matches in SemOpenAlex for { <https://semopenalex.org/work/W4313487454> ?p ?o ?g. }
- W4313487454 endingPage "326" @default.
- W4313487454 startingPage "319" @default.
- W4313487454 abstract "To assess the cost-utility of initial treatment with drug-eluting microspheres (DEM) transarterial chemoembolization (TACE) versus conventional (C)-TACE in patients with hepatocellular carcinoma considering the perspective of a Local Healthcare Authority in Italy.The economic evaluation is based on a retrospective single-center study and individual patients' data whose details have been previously reported. The impact of initial treatment with DEM-TACE or C-TACE on disease progression, mortality, and direct health costs over a lifetime horizon were simulated and compared in terms of incremental cost-utility ratio expressed as costs per quality adjusted life years (QALY). Costs included direct health costs related to the first chemoembolization procedure and all subsequent follow-up costs associated with health care resources used for disease management. Probabilistic (PSA) sensitivity analysis was used to assess the robustness of the results.A total of 101 patients in each treatment group were considered. All over the time-horizon median costs were €3,145.14 and €2,158.32 in the DEM-TACE and C-TACE group, respectively (p < 0.001); while mean costs were € 24,619 and € 17,001, respectively (p < 0.001). The ICUR was 6,461.86 €/QALY when using median costs derived from the study population as input for the health-economic evaluation and 49,932.15 €/QALY when the mean costs were considered. Results from PSA highlighted that using median costs DEM-TACE was always cost-effective, while using mean costs, it was preferable only 24.7% of times.The higher prices of DEMs are counterbalanced by the positive impact on QALY." @default.
- W4313487454 created "2023-01-06" @default.
- W4313487454 creator A5011265052 @default.
- W4313487454 creator A5025048622 @default.
- W4313487454 creator A5031623451 @default.
- W4313487454 creator A5076872354 @default.
- W4313487454 creator A5081162921 @default.
- W4313487454 date "2023-01-04" @default.
- W4313487454 modified "2023-10-18" @default.
- W4313487454 title "Drug-eluting Microspheres Compared to Conventional Transarterial Chemoembolization as First Line Treatment for Unresectable Hepatocellular Carcinoma: A Single-center Retrospective Cost-utility Analysis" @default.
- W4313487454 cites W1605854125 @default.
- W4313487454 cites W166560170 @default.
- W4313487454 cites W1975154077 @default.
- W4313487454 cites W2010265466 @default.
- W4313487454 cites W2021471642 @default.
- W4313487454 cites W2027866182 @default.
- W4313487454 cites W2028319026 @default.
- W4313487454 cites W2036304264 @default.
- W4313487454 cites W2039620750 @default.
- W4313487454 cites W2040633239 @default.
- W4313487454 cites W2052552898 @default.
- W4313487454 cites W2092759077 @default.
- W4313487454 cites W2125763116 @default.
- W4313487454 cites W2141444851 @default.
- W4313487454 cites W2407818042 @default.
- W4313487454 cites W2546747096 @default.
- W4313487454 cites W2557708440 @default.
- W4313487454 cites W2606367731 @default.
- W4313487454 cites W2982183851 @default.
- W4313487454 cites W2990830293 @default.
- W4313487454 cites W2997727194 @default.
- W4313487454 cites W3154388158 @default.
- W4313487454 cites W3157922700 @default.
- W4313487454 cites W3208389663 @default.
- W4313487454 cites W4210955410 @default.
- W4313487454 cites W4242769447 @default.
- W4313487454 cites W77270962 @default.
- W4313487454 doi "https://doi.org/10.1007/s00270-022-03335-4" @default.
- W4313487454 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36599950" @default.
- W4313487454 hasPublicationYear "2023" @default.
- W4313487454 type Work @default.
- W4313487454 citedByCount "0" @default.
- W4313487454 crossrefType "journal-article" @default.
- W4313487454 hasAuthorship W4313487454A5011265052 @default.
- W4313487454 hasAuthorship W4313487454A5025048622 @default.
- W4313487454 hasAuthorship W4313487454A5031623451 @default.
- W4313487454 hasAuthorship W4313487454A5076872354 @default.
- W4313487454 hasAuthorship W4313487454A5081162921 @default.
- W4313487454 hasBestOaLocation W43134874541 @default.
- W4313487454 hasConcept C112930515 @default.
- W4313487454 hasConcept C121955636 @default.
- W4313487454 hasConcept C126322002 @default.
- W4313487454 hasConcept C126838900 @default.
- W4313487454 hasConcept C141071460 @default.
- W4313487454 hasConcept C142724271 @default.
- W4313487454 hasConcept C144133560 @default.
- W4313487454 hasConcept C162324750 @default.
- W4313487454 hasConcept C167135981 @default.
- W4313487454 hasConcept C175444787 @default.
- W4313487454 hasConcept C182299520 @default.
- W4313487454 hasConcept C194828623 @default.
- W4313487454 hasConcept C2776125615 @default.
- W4313487454 hasConcept C2778019345 @default.
- W4313487454 hasConcept C2780073493 @default.
- W4313487454 hasConcept C2908647359 @default.
- W4313487454 hasConcept C3019080777 @default.
- W4313487454 hasConcept C6964187 @default.
- W4313487454 hasConcept C71924100 @default.
- W4313487454 hasConcept C99454951 @default.
- W4313487454 hasConceptScore W4313487454C112930515 @default.
- W4313487454 hasConceptScore W4313487454C121955636 @default.
- W4313487454 hasConceptScore W4313487454C126322002 @default.
- W4313487454 hasConceptScore W4313487454C126838900 @default.
- W4313487454 hasConceptScore W4313487454C141071460 @default.
- W4313487454 hasConceptScore W4313487454C142724271 @default.
- W4313487454 hasConceptScore W4313487454C144133560 @default.
- W4313487454 hasConceptScore W4313487454C162324750 @default.
- W4313487454 hasConceptScore W4313487454C167135981 @default.
- W4313487454 hasConceptScore W4313487454C175444787 @default.
- W4313487454 hasConceptScore W4313487454C182299520 @default.
- W4313487454 hasConceptScore W4313487454C194828623 @default.
- W4313487454 hasConceptScore W4313487454C2776125615 @default.
- W4313487454 hasConceptScore W4313487454C2778019345 @default.
- W4313487454 hasConceptScore W4313487454C2780073493 @default.
- W4313487454 hasConceptScore W4313487454C2908647359 @default.
- W4313487454 hasConceptScore W4313487454C3019080777 @default.
- W4313487454 hasConceptScore W4313487454C6964187 @default.
- W4313487454 hasConceptScore W4313487454C71924100 @default.
- W4313487454 hasConceptScore W4313487454C99454951 @default.
- W4313487454 hasIssue "3" @default.
- W4313487454 hasLocation W43134874541 @default.
- W4313487454 hasLocation W43134874542 @default.
- W4313487454 hasLocation W43134874543 @default.
- W4313487454 hasOpenAccess W4313487454 @default.
- W4313487454 hasPrimaryLocation W43134874541 @default.
- W4313487454 hasRelatedWork W1983012549 @default.
- W4313487454 hasRelatedWork W2003938723 @default.
- W4313487454 hasRelatedWork W2047967234 @default.