Matches in SemOpenAlex for { <https://semopenalex.org/work/W4313487952> ?p ?o ?g. }
- W4313487952 endingPage "107718" @default.
- W4313487952 startingPage "107718" @default.
- W4313487952 abstract "SARS-CoV-2 wastewater-based surveillance (WBS) offers a tool for cost-effective oversight of a population's infections. In the past two years, WBS has proven to be crucial for managing the pandemic across different geographical regions. However, the changing context of the pandemic due to high levels of COVID-19 vaccination warrants a closer examination of its implication towards SARS-CoV-2 WBS. Two main questions were raised: 1) Does vaccination cause shedding of viral signatures without infection? 2) Does vaccination affect the relationship between wastewater and clinical data? To answer, we review historical reports of shedding from viral vaccines in use prior to the COVID-19 pandemic including for polio, rotavirus, influenza and measles infection and provide a perspective on the implications of different COVID-19 vaccination strategies with regard to the potential shedding of viral signatures into the sewershed. Additionally, we reviewed studies that looked into the relationship between wastewater and clinical data and how vaccination campaigns could have affected the relationship. Finally, analyzing wastewater and clinical data from the Netherlands, we observed changes in the relationship concomitant with increasing vaccination coverage and switches in dominant variants of concern. First, that no vaccine-derived shedding is expected from the current commercial pipeline of COVID-19 vaccines that may confound interpretation of WBS data. Secondly, that breakthrough infections from vaccinated individuals contribute significantly to wastewater signals and must be interpreted in light of the changing dynamics of shedding from new variants of concern." @default.
- W4313487952 created "2023-01-06" @default.
- W4313487952 creator A5002121217 @default.
- W4313487952 creator A5004142244 @default.
- W4313487952 creator A5016271328 @default.
- W4313487952 creator A5039241370 @default.
- W4313487952 creator A5044939963 @default.
- W4313487952 creator A5069985129 @default.
- W4313487952 creator A5082344494 @default.
- W4313487952 creator A5083626479 @default.
- W4313487952 creator A5088926769 @default.
- W4313487952 creator A5091119492 @default.
- W4313487952 date "2023-01-01" @default.
- W4313487952 modified "2023-10-16" @default.
- W4313487952 title "Contextualizing Wastewater-Based surveillance in the COVID-19 vaccination era" @default.
- W4313487952 cites W1548214899 @default.
- W4313487952 cites W1815610272 @default.
- W4313487952 cites W1845731828 @default.
- W4313487952 cites W1909274852 @default.
- W4313487952 cites W1924270647 @default.
- W4313487952 cites W1986185553 @default.
- W4313487952 cites W2002631528 @default.
- W4313487952 cites W2015455519 @default.
- W4313487952 cites W2024279068 @default.
- W4313487952 cites W2024467883 @default.
- W4313487952 cites W2031711763 @default.
- W4313487952 cites W2037960557 @default.
- W4313487952 cites W2040968110 @default.
- W4313487952 cites W2044555348 @default.
- W4313487952 cites W2044711900 @default.
- W4313487952 cites W2046253858 @default.
- W4313487952 cites W2050906483 @default.
- W4313487952 cites W2054063508 @default.
- W4313487952 cites W2062942592 @default.
- W4313487952 cites W2065637385 @default.
- W4313487952 cites W2069678021 @default.
- W4313487952 cites W2072115742 @default.
- W4313487952 cites W2079421032 @default.
- W4313487952 cites W2079518804 @default.
- W4313487952 cites W2084753391 @default.
- W4313487952 cites W2090856790 @default.
- W4313487952 cites W2101462714 @default.
- W4313487952 cites W2103463654 @default.
- W4313487952 cites W2106690263 @default.
- W4313487952 cites W2111737459 @default.
- W4313487952 cites W2111816845 @default.
- W4313487952 cites W2126953565 @default.
- W4313487952 cites W2128653614 @default.
- W4313487952 cites W2132072686 @default.
- W4313487952 cites W2132412580 @default.
- W4313487952 cites W2134988341 @default.
- W4313487952 cites W2135983085 @default.
- W4313487952 cites W2143762250 @default.
- W4313487952 cites W2144586605 @default.
- W4313487952 cites W2158756247 @default.
- W4313487952 cites W2160005967 @default.
- W4313487952 cites W2160925265 @default.
- W4313487952 cites W2205901754 @default.
- W4313487952 cites W2219043314 @default.
- W4313487952 cites W2276547831 @default.
- W4313487952 cites W2309518135 @default.
- W4313487952 cites W2313194365 @default.
- W4313487952 cites W2528957557 @default.
- W4313487952 cites W2594592790 @default.
- W4313487952 cites W2613146518 @default.
- W4313487952 cites W2724618708 @default.
- W4313487952 cites W2755447033 @default.
- W4313487952 cites W2758103344 @default.
- W4313487952 cites W2783663318 @default.
- W4313487952 cites W2805721968 @default.
- W4313487952 cites W2898887122 @default.
- W4313487952 cites W2915959809 @default.
- W4313487952 cites W2947446923 @default.
- W4313487952 cites W2952952400 @default.
- W4313487952 cites W2970335474 @default.
- W4313487952 cites W2974248066 @default.
- W4313487952 cites W3011297200 @default.
- W4313487952 cites W3013893137 @default.
- W4313487952 cites W3016746341 @default.
- W4313487952 cites W3017092394 @default.
- W4313487952 cites W3028152077 @default.
- W4313487952 cites W3028495426 @default.
- W4313487952 cites W3036431624 @default.
- W4313487952 cites W3038223917 @default.
- W4313487952 cites W3040390212 @default.
- W4313487952 cites W3041187075 @default.
- W4313487952 cites W3044459694 @default.
- W4313487952 cites W3044763705 @default.
- W4313487952 cites W3046192791 @default.
- W4313487952 cites W3046790002 @default.
- W4313487952 cites W3082385510 @default.
- W4313487952 cites W3084086363 @default.
- W4313487952 cites W3087611057 @default.
- W4313487952 cites W3095861979 @default.
- W4313487952 cites W3111426898 @default.
- W4313487952 cites W3112723974 @default.
- W4313487952 cites W3119084213 @default.
- W4313487952 cites W3119715796 @default.