Matches in SemOpenAlex for { <https://semopenalex.org/work/W4313488198> ?p ?o ?g. }
- W4313488198 abstract "Abstract Guanine quadruplexes (G4s) are nucleic acid structures exhibiting a complex structural behavior and exerting crucial biological functions in both cells and viruses. The specific interactions of peptides with G4s, as well as an understanding of the factors driving the specific recognition are important for the rational design of both therapeutic and diagnostic agents. In this review, we examine the most important studies dealing with the interactions between G4s and peptides, highlighting the strengths and limitations of current analytic approaches. We also show how the combined use of high‐level molecular simulation techniques and experimental spectroscopy is the best avenue to design specifically tuned and selective peptides, thus leading to the control of important biological functions." @default.
- W4313488198 created "2023-01-06" @default.
- W4313488198 creator A5021120930 @default.
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- W4313488198 creator A5036754581 @default.
- W4313488198 creator A5053268362 @default.
- W4313488198 creator A5059227023 @default.
- W4313488198 creator A5083108613 @default.
- W4313488198 date "2023-02-02" @default.
- W4313488198 modified "2023-10-09" @default.
- W4313488198 title "Understanding the Interactions of Guanine Quadruplexes with Peptides as Novel Strategies for Diagnosis or Tuning Biological Functions" @default.
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