Matches in SemOpenAlex for { <https://semopenalex.org/work/W4313488230> ?p ?o ?g. }
- W4313488230 endingPage "4292" @default.
- W4313488230 startingPage "4275" @default.
- W4313488230 abstract "Plants produce biologically active metabolites that have been utilised to cure a variety of severe and persistent illnesses. There is a possibility that understanding how these bioactive molecules work would allow researchers to come up with better treatments for diseases including malignancy, cardiac disease and neurological disorders. A triterpene called ursolic acid (UA) is a pentacyclic prevalent triterpenoid found in fruits, leaves, herbs and blooms. The biological and chemical aspects of UA, as well as their presence, plant sources and biosynthesis, and traditional and newer technologies of extraction, are discussed in this review. Because of its biological function in the creation of new therapeutic techniques, UA is a feasible option for the evolution and medical management of a wide range of medical conditions, including cancer and other life threatening diseases. Despite this, the substance's poor solubility in aquatic environments makes it unsuitable for medicinal purposes. This hurdle was resolved in many different ways. The inclusion of UA into various pharmaceutical delivery approaches was found to be quite effective in this respect. This review also describes the properties of UA and its pharmacokinetics, as well as therapeutic applications of UA for cancer, inflammatory and cardiovascular diseases, in addition to its anti-diabetic, immunomodulatory, hepatoprotective and anti-microbial properties. Some of the recent findings related to novel nano-sized carriers as a delivery system for UA and the patents related to the applications of UA and its various derivatives are covered in this review. The analytical study of UA, oleanolic acid and other phytoconstituents by UV, HPLC, high-performance thin-layer chromatography and gas chromatography is also discussed. In the future, UA could be explored in vivo using various animal models and, in addition, the regulatory status regarding UA needs to be explored. © 2023 Society of Chemical Industry." @default.
- W4313488230 created "2023-01-06" @default.
- W4313488230 creator A5007889615 @default.
- W4313488230 creator A5047917215 @default.
- W4313488230 creator A5060863459 @default.
- W4313488230 creator A5072812895 @default.
- W4313488230 creator A5079746189 @default.
- W4313488230 creator A5082647152 @default.
- W4313488230 date "2023-01-24" @default.
- W4313488230 modified "2023-10-12" @default.
- W4313488230 title "Therapeutic potential and novel formulations of ursolic acid and its derivatives: an updated review" @default.
- W4313488230 cites W1913371122 @default.
- W4313488230 cites W1928078716 @default.
- W4313488230 cites W1969955892 @default.
- W4313488230 cites W1973821570 @default.
- W4313488230 cites W1974259517 @default.
- W4313488230 cites W1988193891 @default.
- W4313488230 cites W1988901228 @default.
- W4313488230 cites W1988978162 @default.
- W4313488230 cites W1995956044 @default.
- W4313488230 cites W1997263440 @default.
- W4313488230 cites W1999957284 @default.
- W4313488230 cites W2003265402 @default.
- W4313488230 cites W2003335151 @default.
- W4313488230 cites W2009763756 @default.
- W4313488230 cites W2009939017 @default.
- W4313488230 cites W2010095445 @default.
- W4313488230 cites W2017698625 @default.
- W4313488230 cites W2019565926 @default.
- W4313488230 cites W2019653365 @default.
- W4313488230 cites W2021194666 @default.
- W4313488230 cites W2022061251 @default.
- W4313488230 cites W2023026415 @default.
- W4313488230 cites W2028045356 @default.
- W4313488230 cites W2029283570 @default.
- W4313488230 cites W2032599628 @default.
- W4313488230 cites W2041497636 @default.
- W4313488230 cites W2063822371 @default.
- W4313488230 cites W2066161414 @default.
- W4313488230 cites W2067555954 @default.
- W4313488230 cites W2068801824 @default.
- W4313488230 cites W2075241862 @default.
- W4313488230 cites W2092964734 @default.
- W4313488230 cites W2093755380 @default.
- W4313488230 cites W2123663431 @default.
- W4313488230 cites W2124290377 @default.
- W4313488230 cites W2140206850 @default.
- W4313488230 cites W2141589119 @default.
- W4313488230 cites W2142665528 @default.
- W4313488230 cites W2156645547 @default.
- W4313488230 cites W2158359278 @default.
- W4313488230 cites W2233813090 @default.
- W4313488230 cites W2255334909 @default.
- W4313488230 cites W2323947639 @default.
- W4313488230 cites W2530130015 @default.
- W4313488230 cites W2538614611 @default.
- W4313488230 cites W2590413844 @default.
- W4313488230 cites W2734681302 @default.
- W4313488230 cites W2767248769 @default.
- W4313488230 cites W2793402252 @default.
- W4313488230 cites W2912331311 @default.
- W4313488230 cites W2914150597 @default.
- W4313488230 cites W2984564814 @default.
- W4313488230 cites W3011560755 @default.
- W4313488230 cites W3011997044 @default.
- W4313488230 cites W3016050883 @default.
- W4313488230 cites W3088184008 @default.
- W4313488230 cites W3120091013 @default.
- W4313488230 cites W3138613643 @default.
- W4313488230 cites W3139174439 @default.
- W4313488230 cites W3212616655 @default.
- W4313488230 cites W4225393487 @default.
- W4313488230 cites W4229006512 @default.
- W4313488230 cites W4280615415 @default.
- W4313488230 cites W4282834048 @default.
- W4313488230 cites W4283766463 @default.
- W4313488230 cites W4298111406 @default.
- W4313488230 doi "https://doi.org/10.1002/jsfa.12423" @default.
- W4313488230 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36597140" @default.
- W4313488230 hasPublicationYear "2023" @default.
- W4313488230 type Work @default.
- W4313488230 citedByCount "4" @default.
- W4313488230 countsByYear W43134882302023 @default.
- W4313488230 crossrefType "journal-article" @default.
- W4313488230 hasAuthorship W4313488230A5007889615 @default.
- W4313488230 hasAuthorship W4313488230A5047917215 @default.
- W4313488230 hasAuthorship W4313488230A5060863459 @default.
- W4313488230 hasAuthorship W4313488230A5072812895 @default.
- W4313488230 hasAuthorship W4313488230A5079746189 @default.
- W4313488230 hasAuthorship W4313488230A5082647152 @default.
- W4313488230 hasConcept C142724271 @default.
- W4313488230 hasConcept C185592680 @default.
- W4313488230 hasConcept C204787440 @default.
- W4313488230 hasConcept C2778858181 @default.
- W4313488230 hasConcept C2779513101 @default.
- W4313488230 hasConcept C2994380890 @default.
- W4313488230 hasConcept C43617362 @default.
- W4313488230 hasConcept C556039675 @default.