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- W4313489970 abstract "In this issue, Chen et al.1 show that genetic knockout of Piezo2 in SOX2+ medulloblastoma cells decreased local tissue stiffness, increased drug delivery across the blood-tumor barrier, and improved survival, uncovering a mechanosensitivity-dependent mechanism of action in a mouse model of pediatric brain tumors." @default.
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- W4313489970 date "2023-01-01" @default.
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- W4313489970 title "Breaking down the barrier to medulloblastoma treatment: Piezo2 knockout disrupts the BTB and increases vascular permeability" @default.
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- W4313489970 doi "https://doi.org/10.1016/j.neuron.2022.12.008" @default.
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