Matches in SemOpenAlex for { <https://semopenalex.org/work/W4313490996> ?p ?o ?g. }
- W4313490996 abstract "Abstract Dysregulated epigenetic modifications dynamically drive the abnormal transcription process to affect the tumor microenvironment; thus, promoting cancer progression, drug resistance, and metastasis. Nowadays, therapies targeting epigenetic dysregulation of tumor cells and immune cells in the tumor microenvironment appear to be promising adjuncts to other cancer therapies. However, the clinical results of combination therapies containing epigenetic agents are disappointing due to systemic toxicities and limited curative effects. Here, the role of epigenetic processes, including DNA methylation, post‐translational modification of histones, and noncoding RNAs is discussed, followed by detailed descriptions of epigenetic regulation of the tumor microenvironment, as well as the application of epigenetic modulators in antitumor therapy, with an emphasis on the epigenetic‐based advanced drug delivery system in targeting the tumor microenvironment." @default.
- W4313490996 created "2023-01-06" @default.
- W4313490996 creator A5004775159 @default.
- W4313490996 creator A5018222046 @default.
- W4313490996 creator A5045895961 @default.
- W4313490996 creator A5060259824 @default.
- W4313490996 date "2023-01-04" @default.
- W4313490996 modified "2023-10-14" @default.
- W4313490996 title "Emerging Epigenetic‐Based Nanotechnology for Cancer Therapy: Modulating the Tumor Microenvironment" @default.
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