Matches in SemOpenAlex for { <https://semopenalex.org/work/W4313503239> ?p ?o ?g. }
- W4313503239 abstract "Triplex-forming oligonucleotides (TFOs) can bind to the major groove of double-stranded DNA with high specificity and affinity and inhibit gene expression. Triplex-forming oligonucleotides have gained prominence because of their potential applications in antigene therapy. In particular, the target specificity of triplex-forming oligonucleotides combined with their ability to suppress oncogene expression has driven their development as anti-cancer agents. So far, triplex-forming oligonucleotides have not been used for clinical treatment and seem to be gradually snubbed in recent years. But triplex-forming oligonucleotides still represent an approach to down-regulate the expression of the target gene and a carrier of active substances. Therefore, in the present review, we will introduce the characteristics of triplex-forming oligonucleotides and their anti-cancer research progress. Then, we will discuss the challenges in their application." @default.
- W4313503239 created "2023-01-06" @default.
- W4313503239 creator A5001099788 @default.
- W4313503239 creator A5013332949 @default.
- W4313503239 creator A5017286506 @default.
- W4313503239 creator A5033009443 @default.
- W4313503239 creator A5033276244 @default.
- W4313503239 creator A5034711601 @default.
- W4313503239 creator A5056273613 @default.
- W4313503239 creator A5069849278 @default.
- W4313503239 date "2022-12-21" @default.
- W4313503239 modified "2023-10-14" @default.
- W4313503239 title "Triplex-forming oligonucleotides as an anti-gene technique for cancer therapy" @default.
- W4313503239 cites W143485405 @default.
- W4313503239 cites W1901604477 @default.
- W4313503239 cites W1969794981 @default.
- W4313503239 cites W1980469270 @default.
- W4313503239 cites W1985528960 @default.
- W4313503239 cites W1986267994 @default.
- W4313503239 cites W1986682897 @default.
- W4313503239 cites W1988011340 @default.
- W4313503239 cites W1988051735 @default.
- W4313503239 cites W1994421111 @default.
- W4313503239 cites W1994862860 @default.
- W4313503239 cites W2004059420 @default.
- W4313503239 cites W2010731690 @default.
- W4313503239 cites W2012488414 @default.
- W4313503239 cites W2023036582 @default.
- W4313503239 cites W2023444646 @default.
- W4313503239 cites W2027287031 @default.
- W4313503239 cites W2029145757 @default.
- W4313503239 cites W2031662478 @default.
- W4313503239 cites W2033018487 @default.
- W4313503239 cites W2038750251 @default.
- W4313503239 cites W2045460763 @default.
- W4313503239 cites W2055553682 @default.
- W4313503239 cites W2056020967 @default.
- W4313503239 cites W2056579307 @default.
- W4313503239 cites W2057734086 @default.
- W4313503239 cites W2060640204 @default.
- W4313503239 cites W2070235053 @default.
- W4313503239 cites W2072742143 @default.
- W4313503239 cites W2086212674 @default.
- W4313503239 cites W2086424237 @default.
- W4313503239 cites W2091883424 @default.
- W4313503239 cites W2098924171 @default.
- W4313503239 cites W2107664182 @default.
- W4313503239 cites W2111543678 @default.
- W4313503239 cites W2119121123 @default.
- W4313503239 cites W2119970960 @default.
- W4313503239 cites W2122615155 @default.
- W4313503239 cites W2127268764 @default.
- W4313503239 cites W2132638593 @default.
- W4313503239 cites W2133779768 @default.
- W4313503239 cites W2133918133 @default.
- W4313503239 cites W2146711684 @default.
- W4313503239 cites W2148611875 @default.
- W4313503239 cites W2152368724 @default.
- W4313503239 cites W2158138924 @default.
- W4313503239 cites W2165139981 @default.
- W4313503239 cites W2172158357 @default.
- W4313503239 cites W2174153541 @default.
- W4313503239 cites W2178707023 @default.
- W4313503239 cites W2300340713 @default.
- W4313503239 cites W2321608539 @default.
- W4313503239 cites W2326493716 @default.
- W4313503239 cites W2409992729 @default.
- W4313503239 cites W2468911720 @default.
- W4313503239 cites W2500192509 @default.
- W4313503239 cites W2754336033 @default.
- W4313503239 cites W2775457730 @default.
- W4313503239 cites W2888758890 @default.
- W4313503239 cites W2977428256 @default.
- W4313503239 cites W3004561117 @default.
- W4313503239 cites W3006069730 @default.
- W4313503239 cites W3006800369 @default.
- W4313503239 cites W3009456063 @default.
- W4313503239 cites W3044398778 @default.
- W4313503239 cites W3047226532 @default.
- W4313503239 cites W3093200681 @default.
- W4313503239 cites W3130709842 @default.
- W4313503239 cites W3180795098 @default.
- W4313503239 cites W3206453522 @default.
- W4313503239 cites W3208370655 @default.
- W4313503239 cites W329007366 @default.
- W4313503239 cites W39164435 @default.
- W4313503239 cites W4205502918 @default.
- W4313503239 cites W4256296369 @default.
- W4313503239 doi "https://doi.org/10.3389/fphar.2022.1007723" @default.
- W4313503239 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36618947" @default.
- W4313503239 hasPublicationYear "2022" @default.
- W4313503239 type Work @default.
- W4313503239 citedByCount "6" @default.
- W4313503239 countsByYear W43135032392023 @default.
- W4313503239 crossrefType "journal-article" @default.
- W4313503239 hasAuthorship W4313503239A5001099788 @default.
- W4313503239 hasAuthorship W4313503239A5013332949 @default.
- W4313503239 hasAuthorship W4313503239A5017286506 @default.
- W4313503239 hasAuthorship W4313503239A5033009443 @default.
- W4313503239 hasAuthorship W4313503239A5033276244 @default.