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- W4313503753 abstract "Five natural secondary metabolites as cinnamic acid (1), (+)-catechin (2), (-)-epicatechin (3), p-coumaric acid (4), and ferulic acid (5) were isolated from Amanita caesarea based on anti-inflammatory activity-guided extraction. Their structures (1-5) were determined by NMR spectra as well as by comparison with previously reported literature. Compounds 3 and 5 have been isolated from A. caesarea for the first time. The anti-inflammatory activity through inhibition of nitric oxide (NO) production of isolates (1-5) was evaluated. Among them, compounds 2 and 3 exhibited strong inhibitory activity with IC50 values of 4.8 and 5.7 μM, respectively. Compounds 4 and 5 with IC50 values of 18.4 and 9.6 μM, respectively showed moderate inhibitory activity. The results proposed that A. caesarea might exert anti-inflammatory effects due to its mainly NO-inhibitory constituents" @default.
- W4313503753 created "2023-01-06" @default.
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- W4313503753 date "2022-12-31" @default.
- W4313503753 modified "2023-09-30" @default.
- W4313503753 title "Anti-inflammatory activities of compounds isolated from Amanita caesarea collected in Lam Dong province" @default.
- W4313503753 doi "https://doi.org/10.31130/ud-jst.2022.295e" @default.
- W4313503753 hasPublicationYear "2022" @default.
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