FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4313505505> ?p ?o ?g. }

• W4313505505 endingPage "127" @default.
• W4313505505 startingPage "127" @default.
• W4313505505 abstract "(1) Interest in the Juncaceae family has risen as some members have shown anti-inflammatory properties and interesting compounds. In this regard, we decided to investigate the antioxidant and anti-inflammatory properties of Luzula sylvatica, a Juncaceae not yet extensively studied, in the context of osteoarthritis. (2) The Luzula sylvatica Ethanol extract (LS-E) was used to test the production of reactive oxygen species (ROS) by leucocytes, the IL1β and PGE2 production by peripheral blood mononuclear cells (PBMCs), the production of EP4, and the activation of NFκB in THP-1, as well as the IL1β-activated normal human knee articular chondrocytes (NHAC-Kn) gene expression, grown in monolayers or maintained in alginate beads. (3) Organic acids, caffeoylquinic acids, quercetin and luteolin, compounds frequently found in this family were identified. The LS-E exhibited inhibited ROS formation. The LS-E did not affect NFκB activation and IL1β secretion but dampened the secretion of PGE2 by PBMCs and the presence of EP4 in THP-1. It also modulated the expression of NHAC-Kn in both models and inhibited the expression of several proteases and inflammatory mediators. (4) Luzula sylvatica might supply interesting antioxidant protection against cartilage damages and lessen joint inflammation, notably by decreasing PGE2 secretion in the synovial fluid. Moreover, it could act directly on chondrocytes by decreasing the expression of proteases and, thus, preventing the degradation of the extracellular matrix." @default.
• W4313505505 created "2023-01-06" @default.
• W4313505505 creator A5001557778 @default.
• W4313505505 creator A5006680609 @default.
• W4313505505 creator A5009414130 @default.
• W4313505505 creator A5010610129 @default.
• W4313505505 creator A5011844964 @default.
• W4313505505 creator A5013287185 @default.
• W4313505505 creator A5019352730 @default.
• W4313505505 creator A5022872903 @default.
• W4313505505 creator A5033372653 @default.
• W4313505505 creator A5039091058 @default.
• W4313505505 creator A5045591367 @default.
• W4313505505 creator A5050142232 @default.
• W4313505505 creator A5053783321 @default.
• W4313505505 creator A5057078491 @default.
• W4313505505 creator A5068690496 @default.
• W4313505505 creator A5070318768 @default.
• W4313505505 creator A5077287444 @default.
• W4313505505 creator A5078250536 @default.
• W4313505505 creator A5080061609 @default.
• W4313505505 creator A5083817004 @default.
• W4313505505 creator A5086518899 @default.
• W4313505505 date "2022-12-21" @default.
• W4313505505 modified "2023-10-18" @default.
• W4313505505 title "Potential Anti-Inflammatory and Chondroprotective Effect of Luzula sylvatica" @default.
• W4313505505 cites W1966276149 @default.
• W4313505505 cites W1972225360 @default.
• W4313505505 cites W1976571994 @default.
• W4313505505 cites W1978943323 @default.
• W4313505505 cites W1993990835 @default.
• W4313505505 cites W2009469478 @default.
• W4313505505 cites W2011127593 @default.
• W4313505505 cites W2011867519 @default.
• W4313505505 cites W2020173353 @default.
• W4313505505 cites W2028284622 @default.
• W4313505505 cites W2044812471 @default.
• W4313505505 cites W2050148742 @default.
• W4313505505 cites W2071881303 @default.
• W4313505505 cites W2073014687 @default.
• W4313505505 cites W2074818019 @default.
• W4313505505 cites W2079228360 @default.
• W4313505505 cites W2087461602 @default.
• W4313505505 cites W2087634393 @default.
• W4313505505 cites W2323052646 @default.
• W4313505505 cites W2400216600 @default.
• W4313505505 cites W2534236383 @default.
• W4313505505 cites W2560789697 @default.
• W4313505505 cites W2584503597 @default.
• W4313505505 cites W2776443743 @default.
• W4313505505 cites W2792740745 @default.
• W4313505505 cites W2889101189 @default.
• W4313505505 cites W2920832988 @default.
• W4313505505 cites W2979976280 @default.
• W4313505505 cites W3007813936 @default.
• W4313505505 cites W3027915885 @default.
• W4313505505 cites W3118868593 @default.
• W4313505505 cites W3136380465 @default.
• W4313505505 cites W3147437354 @default.
• W4313505505 cites W326460509 @default.
• W4313505505 cites W4220718281 @default.
• W4313505505 cites W4283371525 @default.
• W4313505505 doi "https://doi.org/10.3390/ijms24010127" @default.
• W4313505505 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36613576" @default.
• W4313505505 hasPublicationYear "2022" @default.
• W4313505505 type Work @default.
• W4313505505 citedByCount "1" @default.
• W4313505505 countsByYear W43135055052023 @default.
• W4313505505 crossrefType "journal-article" @default.
• W4313505505 hasAuthorship W4313505505A5001557778 @default.
• W4313505505 hasAuthorship W4313505505A5006680609 @default.
• W4313505505 hasAuthorship W4313505505A5009414130 @default.
• W4313505505 hasAuthorship W4313505505A5010610129 @default.
• W4313505505 hasAuthorship W4313505505A5011844964 @default.
• W4313505505 hasAuthorship W4313505505A5013287185 @default.
• W4313505505 hasAuthorship W4313505505A5019352730 @default.
• W4313505505 hasAuthorship W4313505505A5022872903 @default.
• W4313505505 hasAuthorship W4313505505A5033372653 @default.
• W4313505505 hasAuthorship W4313505505A5039091058 @default.
• W4313505505 hasAuthorship W4313505505A5045591367 @default.
• W4313505505 hasAuthorship W4313505505A5050142232 @default.
• W4313505505 hasAuthorship W4313505505A5053783321 @default.
• W4313505505 hasAuthorship W4313505505A5057078491 @default.
• W4313505505 hasAuthorship W4313505505A5068690496 @default.
• W4313505505 hasAuthorship W4313505505A5070318768 @default.
• W4313505505 hasAuthorship W4313505505A5077287444 @default.
• W4313505505 hasAuthorship W4313505505A5078250536 @default.
• W4313505505 hasAuthorship W4313505505A5080061609 @default.
• W4313505505 hasAuthorship W4313505505A5083817004 @default.
• W4313505505 hasAuthorship W4313505505A5086518899 @default.
• W4313505505 hasBestOaLocation W43135055051 @default.
• W4313505505 hasConcept C151730666 @default.
• W4313505505 hasConcept C164027704 @default.
• W4313505505 hasConcept C181199279 @default.
• W4313505505 hasConcept C182220744 @default.
• W4313505505 hasConcept C185592680 @default.
• W4313505505 hasConcept C203014093 @default.
• W4313505505 hasConcept C2776914184 @default.

• next