Matches in SemOpenAlex for { <https://semopenalex.org/work/W4313509688> ?p ?o ?g. }
- W4313509688 endingPage "354" @default.
- W4313509688 startingPage "354" @default.
- W4313509688 abstract "Cross-sectional imaging is the standard diagnostic tool to determine underlying biology in renal masses, which is crucial for subsequent treatment. Currently, standard CT imaging is limited in its ability to differentiate benign from malignant disease. Therefore, various modalities have been investigated to identify imaging-based parameters to improve the noninvasive diagnosis of renal masses and renal cell carcinoma (RCC) subtypes. MRI was reported to predict grading of RCC and to identify RCC subtypes, and has been shown in a small cohort to predict the response to targeted therapy. Dynamic imaging is promising for the staging and diagnosis of RCC. PET/CT radiotracers, such as 18F-fluorodeoxyglucose (FDG), 124I-cG250, radiolabeled prostate-specific membrane antigen (PSMA), and 11C-acetate, have been reported to improve the identification of histology, grading, detection of metastasis, and assessment of response to systemic therapy, and to predict oncological outcomes. Moreover, 99Tc-sestamibi and SPECT scans have shown promising results in distinguishing low-grade RCC from benign lesions. Radiomics has been used to further characterize renal masses based on semantic and textural analyses. In preliminary studies, integrated machine learning algorithms using radiomics proved to be more accurate in distinguishing benign from malignant renal masses compared to radiologists’ interpretations. Radiomics and radiogenomics are used to complement risk classification models to predict oncological outcomes. Imaging-based biomarkers hold strong potential in RCC, but require standardization and external validation before integration into clinical routines." @default.
- W4313509688 created "2023-01-06" @default.
- W4313509688 creator A5014108239 @default.
- W4313509688 creator A5062779261 @default.
- W4313509688 creator A5081768872 @default.
- W4313509688 creator A5089094298 @default.
- W4313509688 creator A5090987054 @default.
- W4313509688 date "2023-01-05" @default.
- W4313509688 modified "2023-10-16" @default.
- W4313509688 title "Advances in Imaging-Based Biomarkers in Renal Cell Carcinoma: A Critical Analysis of the Current Literature" @default.
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