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- W4313532375 abstract "Multi-layer Complex networks are commonly used for modeling and analysing biological entities. This paper presents a new computational framework called COMBO (Combining Multi Bio Omics) for generating and analyzing heterogeneous multi-layer networks. Our model uses gene expression and DNA-methylation data. The power of COMBO relies on its ability to join different omics to study the complex interplay between various components in the disease. We tested the reliability and versatility of COMBO on colon and lung adenocarcinoma cancer data obtained from the TCGA database." @default.
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- W4313532375 date "2023-01-01" @default.
- W4313532375 modified "2023-10-18" @default.
- W4313532375 title "COMBO: A Computational Framework to Analyze RNA-seq and Methylation Data Through Heterogeneous Multi-layer Networks" @default.
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- W4313532375 doi "https://doi.org/10.1007/978-3-031-21127-0_21" @default.
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